2,5-二甲氧基四氢呋喃合成路线 （共 286 条）
反应条件
sodium tetrahydroborate; sulfuric acid; water in tetrahydrofuran; methanol T=10 - 20°C; 1.5 h; Yields of byproduct given;
参考文献
Verardo, Giancarlo; Dolce, Anna; Toniutti, Nicoletta
Synthesis, 1999 , # 1 p. 74 - 79
反应条件
in water; benzene Heatingother solvents; in the presence of sodium dodecyl sulfate; Product distribution;
参考文献
Kashima, Choji; Hibi, Shigeki; Maruyama, Tatsuya; Harada, Kazuo; Omote, Yoshimori
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 913 - 916
反应条件
phosphorus pentoxide in toluene T=60 - 110°C; 1.25 h;
参考文献
Synthetic Communications, , vol. 25, # 12 p. 1857 - 1861
反应条件
sodium acetate in acetic acid; ethyl acetate
参考文献
Yeda Research and Development Co., Ltd.
Patent: US4148998 A1, 1979 ;
参考文献
Martinez, Gregory R.; Walker, Keith A. M.; Hirschfeld, Donald R.; Maloney, Patrick J.; Yang, Diana S.; Rosenkranz, Roberto P.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 4 p. 890 - 897
反应条件
acetic acid RefluxSealed tube;
参考文献
Lee; Jung; Hahn
Asian Journal of Chemistry, 2013 , vol. 25, # 1 p. 501 - 504
反应条件
acetic acid; triethylamine 5 h; Heating;
参考文献
Negoro, Toshiyuki; Murata, Makoto; Ueda, Shozo; Fujitani, Buichi; Ono, Yoshiyuki; Kuromiya, Akelmi; Komiya, Masanobu; Suzuki, Kenji; Matsumoto, Jun-Ichi
Journal of Medicinal Chemistry, 1998 , vol. 41, # 21 p. 4118 - 4129
反应条件
sodium tetrahydroborate; sulfuric acid; water in tetrahydrofuran; methanol T=10 - 20°C; 1.5 h; Yield given;
参考文献
Verardo, Giancarlo; Dolce, Anna; Toniutti, Nicoletta
Synthesis, 1999 , # 1 p. 74 - 79
反应条件
in water T=150°C; Paal-Knorr condensation; 0.5 h; Microwave irradiation;
参考文献
Wilson, Matthew A.; Filzen, Gary; Welmaker, Gregory S.
Tetrahedron Letters, 2009 , vol. 50, # 34 p. 4807 - 4809
参考文献
Cope; Keller
Journal of Organic Chemistry, 1956 , vol. 21, p. 141
