1,3-苯并二氧戊环-5-羧酸乙酯合成路线 （共 16 条）
参考文献
Delange
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1907 , vol. 144, p. 1278
Bulletin de la Societe Chimique de France, 1908 , vol. <4> 3, p. 509
反应条件
diethyl ether; sodium
参考文献
Bradley; Robinson
Journal of the Chemical Society, 1926 , p. 2363
反应条件
sodium amide; benzene
参考文献
v. Bruchhausen; Lingner
Archiv der Pharmazie (Weinheim, Germany), 1957 , vol. 290, p. 1,11
反应条件
1: With sodium diisobutyl-tert-butoxyaluminium hydride in tetrahydrofuran T=0°C; 4 h; Inert atmosphere; 2: With ammonia; iodine in tetrahydrofuran; water T=0 - 20°C; 3 h;
参考文献
Tetrahedron, , vol. 67, # 41 p. 7956 - 7962
参考文献
Brady; Dunn
Journal of the Chemical Society, 1926 , p. 2414
反应条件
hydrazine hydrate 8 h; Heating;
参考文献
Ke, Shaoyong; Liu, Fengyi; Wang, Ni; Yang, Qing; Qian, Xuhong
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 2 p. 332 - 335
反应条件
palladium (II) trifluoroacetate; 1,3-bis-(diphenylphosphino)propane in 1-methyl-pyrrolidin-2-one
T=150°C; 24 h; Inert atmosphere;
参考文献
Shang, Rui; Fu, Yao; Li, Jia-Bin; Zhang, Song-Lin; Guo, Qing-Xiang; Liu, Lei
Journal of the American Chemical Society, 2009 , vol. 131, p. 5738 - 5739
反应条件
[2,2']bipyridinyl; palladium (II) trifluoroacetate in nitromethane
T=120°C; 48 h; Inert atmosphere;
参考文献
Qian, Cheng; Chen, Jiayan; Fu, Meiqin; Zhu, Shiya; Chen, Wen-Hua; Jiang, Huanfeng; Zeng, Wei
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 36 p. 6013 - 6022
反应条件
thionyl chloride; triethylamine in ethanol
参考文献
Rosales, Carmen Almansa; Gonzalez Gonzalez, Concepcion; Torres Barreda, Maria Carmen
Patent: US2003/176481 A1, 2003 ;
反应条件
1: 1,2-methylenedioxy-4-bromobenzene With magnesium; ethylene dibromide in tetrahydrofuran
1.5 h; sonification;
2: diethyl dicarbonate With boron trifluoride diethyl etherate in tetrahydrofuran
T=20°C; Barbier carboxylation; 5 h;
参考文献
Lee, Adam Shih-Yuan; Wu, Chih-Chiang; Lin, Li-Shin; Hsu, Hsiu-Fu
Synthesis, 2004 , # 4 p. 568 - 572
