反应条件
1: With sodium hydride in N,N-dimethyl-formamide
T=20°C; Inert atmosphere;
2: With butane-1-thiol in N,N-dimethyl-formamide
T=110°C; Cooling with iceInert atmosphere;
3: With water; acetic acid
参考文献
Myllymaeki, Mikko J.; Kaesnaenen, Heikki; Kataja, Antti O.; Lahtela-Kakkonen, Maija; Saario, Susanna M.; Poso, Antti; Koskinen, Ari M.P.
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 10 p. 4179 - 4191