1-甲基-4(1H)-吡啶酮合成路线 （共 16 条）
反应条件
in tetrahydrofuran 2.41667 h; Heating;
参考文献
Aubert, Corinne; Betschmann, Patrick; Eichberg, Michael J.; Gandon, Vincent; Heckrodt, Thilo J.; Lehmann, Juerg; Malacria, Max; Masjost, Birgit; Paredes, Elisa; Vollhardt, K. Peter C.; Whitener, Glenn D.
Chemistry - A European Journal, 2007 , vol. 13, # 26 p. 7443 - 7465
参考文献
Societe Nationale des Poudres et Explosifs
Patent: US4297301 A1, 1981 ;
反应条件
methanol; nickel T=150 - 155°C; P=73550.8 Torr; Hydrogenation;
参考文献
Coan et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 3701
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
The Dow Chemical Company
Patent: US4595763 A1, 1986 ;
反应条件
in acetonitrile
T=80°C; 24 h; Inert atmosphere; regioselective reaction;
参考文献
Heller, Stephen T.; Sarpong, Richmond
Tetrahedron, 2011 , vol. 67, # 46 p. 8851 - 8859
反应条件
n-Pentyl nitrite; sodium ethanolate in ethanol
1.) 0-5 deg C, 2 h, 2.) reflux, 3 h;
参考文献
Katritzky, Alan R.; Patel, Ranjan C.; Shanta, Mohammed
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1888 - 1889
反应条件
triphenylemethane in dimethyl sulfoxide
T=230°C; 40 h;
参考文献
Yeoh, Fong Ying; Cuasito, Roxanne R.; Capule, Christina C.; Wong, Freeman M.; Wu, Weiming
Bioorganic Chemistry, 2007 , vol. 35, # 4 p. 338 - 343
反应条件
methanol; potassium hydroxide
参考文献
Haitinger; Lieben
Monatshefte fuer Chemie, 1885 , vol. 6, p. 312
参考文献
Haitinger; Lieben
Monatshefte fuer Chemie, 1885 , vol. 6, p. 315
Chemische Berichte, 1885 , vol. 18, p. 930
反应条件
potassium carbonate
1.) 0 deg C, 2 h, 2.) CH3OH, 30 min; Yield given. Multistep reaction;
参考文献
Guerry, Philippe; Neier, Reinhard
Synthesis, 1984 , # 6 p. 485 - 488
