6-硝基喹唑啉-4(3H)-酮合成路线 （共 34 条）
参考文献
HANMI PHARM. CO., LTD.
Patent: WO2006/71017 A1, 2006 ;
Location in patent: Page/Page column 34 ;
WO 2006/071017 A1
反应条件
hydrogenchloride T=20°C; 1.5 h;
参考文献
Tobe, Masanori; Isobe, Yoshiaki; Tomizawa, Hideyuki; Nagasaki, Takahiro; Takahashi, Hirotada; Fukazawa, Tominaga; Hayashi, Hideya
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 3 p. 383 - 391
反应条件
sulfuric acid; nitric acid T=95°C; 0.666667 h;
参考文献
Aberg, Ola; Langstroema, Bengt
Journal of Labelled Compounds and Radiopharmaceuticals, 2012 , vol. 55, # 14 p. 477 - 483
参考文献
WO2006/12374 A1, ;
Page/Page column 181 ;
WO 2006/012374 A1
反应条件
T=210°C; Cycloaddition; 0.25 h;
参考文献
Chao, Qi; Deng, Lynn; Shih, Hsiencheng; Leoni, Lorenzo M.; Genini, Davide; Carson, Dennis A.; Cottam, Howard B.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 19 p. 3860 - 3873
反应条件
zinc(II) chloride T=200°C; 5 h; sealed tube;
参考文献
Organic Letters, , vol. 11, # 6 p. 1193 - 1196
反应条件
1: aqueous ammonia; 1-ethyl-3-[(dimethylamino)propyl]carbodiimide; 1-hydroxybenzotriazole / dimethylformamide / 4 h 2: aq. HCl / 1 h View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 11, # 18 p. 3869 - 3878
参考文献
Journal of the Chemical Society, , p. 1104,1111
参考文献
Journal of the Chemical Society, , p. 360,364
反应条件
1: 7 h / 130 °C 2: nitric acid; sulfuric acid / 0.67 h / 95 °C View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 55, # 14 p. 477 - 483
