双环[2.2.1]庚-5-烯-2-酮合成路线 （共 39 条）
反应条件
3,3,4,4-tetramethyl-1,2-dioxetane in benzene T=85°C; 1.5 h; Product distribution;
参考文献
Chemische Berichte, , vol. 118, # 8 p. 3070 - 3088
反应条件
chromium(VI) oxide; sodium hydroxide 1) water, photolysis, 2) CH2Cl2, pyridine, r.t., 125 min; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Chemische Berichte, , vol. 114, # 3 p. 1187 - 1191
反应条件
perchloric acid; sodium nitrite in water 30 h; Ambient temperature; Product distribution;
参考文献
Chemische Berichte, , vol. 114, # 3 p. 1187 - 1191
反应条件
T=300°C; P=22 Torr; Product distribution;
参考文献
Chemische Berichte, , vol. 118, # 8 p. 3070 - 3088
参考文献
Tetrahedron Letters, , vol. 21, p. 755 - 758
参考文献
Tetrahedron Letters, , vol. 21, p. 755 - 758
反应条件
1: 77 percent / L-selectride / tetrahydrofuran / -78 - -20 °C 2: 78 percent / pyridine; dimethylaminopyridine / CH2Cl2 / 20 h / 20 °C View Scheme
参考文献
Gustavsson, Anna-Lena; Larsson, Mattias C.; Hansson, Bill S.; Liljefors, Tommy
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 12 p. 2173 - 2183
反应条件
phosphorus pentachloride; potassium tert-butylate Ambient temperature1) CCl4, 15 h, 2) DMSO, 1 h; Yield given. Title compound not separated from byproducts;
参考文献
Baumgaertel, Otto; Szeimies, Guenter
Chemische Berichte, 1983 , vol. 116, # 6 p. 2180 - 2204
反应条件
potassium tert-butylate; water in dimethyl sulfoxide Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Lajunen, Martti; Lahti, Marjo; Heimo, Satu
Acta Chemica Scandinavica, 1989 , vol. 43, # 8 p. 771 - 776
反应条件
toluene-4-sulfonic acid in benzene 60 h; Heating / reflux;
参考文献
TARGACEPT, INC.
Patent: WO2005/37832 A2, 2005 ;
Location in patent: Page/Page column 80 ;
WO 2005/037832 A2
