双环[2,2,1]庚烯-7-酮合成路线 （共 5 条）
参考文献
Mieusset, Jean-Luc; Bespokoev, Alexander; Pacar, Mirjana; Abraham, Michael; Arion, Vladimir B.; Brinker, Udo H.
Journal of Organic Chemistry, 2008 , vol. 73, # 17 p. 6551 - 6558
反应条件
toluene-4-sulfonic acid in benzene 4 h; Heating;
参考文献
Fujita, Toshiaki; Tanaka, Masakazu; Norimine, Yoshihiko; Suemune, Hiroshi; Sakai, Kiyoshi
Journal of Organic Chemistry, 1997 , vol. 62, # 12 p. 3824 - 3830
反应条件
1: tetrahydrofuran / -78 °C
2: 1.) sodium hydride / 1.) 0 deg C, 0.5 h, 2.) room temperature, 20 h
3: 95 percent / hydrogen / 10percent palladium on charcoal / ethyl acetate / 7 h
4: sodium/potassium alloy / tetrahydrofuran / 1 h / -10 - -5 °C / 0 Torr
5: 55 percent / methanol
View Scheme
参考文献
Peoples,P.R.; Grutzner,J.B.
Journal of the American Chemical Society, 1980 , vol. 102, p. 4709
反应条件
sodium hydride in dimethyl sulfoxide
参考文献
Gassman,P.G.; Pascone,J.M.
Journal of the American Chemical Society, 1973 , vol. 95, p. 7801 - 7813
反应条件
1: 78 percent / 2,6-di-tert-butyl-4-methylpyridine / CH2Cl2 / 1 h / Ambient temperature
2: 71 percent / MgI2 / diethyl ether / 24 h / Heating; further reagent; MeMgI
View Scheme
参考文献
Martinez, Antonio Garcia; Rios, Iluminada Espada; Barcina, Jose Osio; Hernando, Manuel Montero
Chemische Berichte, 1984 , vol. 117, # 3 p. 982 - 989
