四氢-2H-吡喃-2-醇合成路线 （共 136 条）
反应条件
sodium hydride; dimethyl sulfoxide
1.) 75 deg C, 30 min, 2.) DMSO, 75 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Hudson, Christine M.; Marzabadi, Mohammad R.; Moeller, Kevin D.; New, Dallas G.
Journal of the American Chemical Society, 1991 , vol. 113, # 19 p. 7372 - 7385
反应条件
boron trifluoride diethyl etherate in chloroform
7 h; Ambient temperature;
参考文献
Rama Rao, A. V.; Deshmukh, M. N.; Sharma, G. V. M.
Tetrahedron, 1987 , vol. 43, # 4 p. 779 - 784
参考文献
Paul
Bulletin de la Societe Chimique de France, 1935 , vol. <5> 2, p. 311,321
Bulletin de la Societe Chimique de France, 1938 , vol. <5> 5, p. 1053,1062
反应条件
in tetrahydrofuran
T=20°C;
参考文献
Yamaguchi, Yumi; Hashimoto, Mariko; Tohyama, Katsumi; Kimura, Masanari
Tetrahedron Letters, 2011 , vol. 52, # 8 p. 913 - 915
反应条件
1: potassium carbonate
2: diethyl ether
View Scheme
参考文献
Gaumeton; Glacet
Bulletin de la Societe Chimique de France, 1959 , p. 1501,1504
反应条件
1: tetrahydrofuran / 1.75 h / below 10 deg C
2: 82 percent Spectr. / 8N CrO3 / acetone / 1 h / 5 - 10 °C
View Scheme
参考文献
Harada, Hironori; Mori, Kenji
Agricultural and Biological Chemistry, 1989 , vol. 53, # 5 p. 1439 - 1440
反应条件
1: tetrahydrofuran / 14 h / Reflux
2: sodium hydride / tetrahydrofuran; mineral oil / 4 h / 0 - 20 °C
View Scheme
参考文献
Berthel, Steven Joseph; Chen, Li; Corbett, Wendy Lea; Feng, LiChun; Haynes, Nancy-Ellen; Kester, Robert Francis; So, Sung-Sau; Tilley, Jefferson Wright
Patent: US2011/144105 A1, 2011 ;
反应条件
sodium methylate in methanol
T=30°C; P=50 Torr; 2 h;
参考文献
Bowen III, Daniel Edward; Castner, Eric Sean
Patent: US2004/87803 A1, 2004 ;
Location in patent: Page 25-26 ;
反应条件
sodium methylate in methanol
T=30°C; P=50 Torr; 2 h;
参考文献
Bowen III, Daniel Edward; Castner, Eric Sean
Patent: US2004/87803 A1, 2004 ;
Location in patent: Page 26 ;
反应条件
1: N-heptyl-triphenylphosphonium bromide With potassium hexamethylsilazane in tetrahydrofuran; toluene
T=0°C; 1.08333 h; Inert atmosphere;
2: tetrahydropyranyl alcohol in tetrahydrofuran; toluene
T=-78 - 20°C; Wittig reaction; Inert atmosphere; stereoselective reaction;
参考文献
Ragoussis, Valentine; Perdikaris, Stamatis; Karamolegkos, Antonis; Magkiosi, Konstantina
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 24 p. 11929 - 11932
