5-甲氧基-N-甲基-3-硝基苯胺合成路线 （共 10 条）
反应条件
potassium carbonate in dichloromethane; water T=20°C; 48 h;
参考文献
Newsome, Jeffery J.; Colucci, Marie A.; Hassani, Mary; Beall, Howard D.; Moody, Christopher J.
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 22 p. 3665 - 3673
反应条件
sodium methylate; dimethyl sulfate in N-methyl-acetamide; methanol; water
参考文献
SANKYO COMPANY, LIMITED
Patent: US2003/8907 A1, 2003 ;
反应条件
hydrogenchloride; sodium chloride in 1,4-dioxane
反应条件
sodium methylate in methanol; DMF (N,N-dimethyl-formamide) T=55°C; 2 h;
参考文献
Sankyo Company, Limited
Patent: EP1191019 A1, 2002 ;
Location in patent: Page 59 ;
反应条件
sodium methylate; methylamine in N,N-dimethyl acetamide; water
反应条件
1: 1-nitro-2,4-dichlorobenzene; methylamine in N,N-dimethyl acetamide T=75 - 80°C; 2 h; 2: sodium methylate in methanol; N,N-dimethyl acetamide T=75 - 80°C; 2.5 h;
参考文献
SANKYO COMPANY, LIMITED; OKAZAKI, Rei; IKEUCHI, Yutaka
Patent: WO2006/35685 A1, 2006 ;
Location in patent: Page/Page column 47 ;
反应条件
water T=120°C; unter Druck;
参考文献
Gazzetta Chimica Italiana, , vol. 85, p. 769,788
反应条件
sulfuric acid; acetic acid
参考文献
Chemische Berichte, , vol. 89, p. 2030,2038
反应条件
2: concentrated H2SO4; acetic acid View Scheme
参考文献
Chemische Berichte, , vol. 89, p. 2030,2038
参考文献
Gazzetta Chimica Italiana, , vol. 85, p. 769,788
