3,4-二氢化-5-甲基-1(2H)-萘酮合成路线 （共 40 条）
反应条件
1: K2CO3 / aq. ethanol / 48 h / Heating
2: polyphosphoric acid / 1 h / 90 - 100 °C
View Scheme
参考文献
Cagniant,P. et al.
Bulletin de la Societe Chimique de France, 1969 , p. 985 - 991
反应条件
1: K2CO3 / aq. ethanol / 48 h / Heating
2: polyphosphoric acid / 1 h / 90 - 100 °C
View Scheme
参考文献
Cagniant,P. et al.
Bulletin de la Societe Chimique de France, 1969 , p. 985 - 991
反应条件
1: (i) LiAlH4, Et2O (ii) HBr, H2SO4, AcOH
2: aq. ethanol
3: K2CO3 / aq. ethanol / 48 h / Heating
4: polyphosphoric acid / 1 h / 90 - 100 °C
View Scheme
参考文献
Cagniant,P. et al.
Bulletin de la Societe Chimique de France, 1969 , p. 985 - 991
反应条件
1: (i) LiAlH4, Et2O (ii) HBr, H2SO4, AcOH
2: aq. ethanol
3: K2CO3 / aq. ethanol / 48 h / Heating
4: polyphosphoric acid / 1 h / 90 - 100 °C
View Scheme
参考文献
Cagniant,P. et al.
Bulletin de la Societe Chimique de France, 1969 , p. 985 - 991
反应条件
1: 150 °C
2: (i) LiAlH4, Et2O (ii) HBr, H2SO4, AcOH
3: aq. ethanol
4: K2CO3 / aq. ethanol / 48 h / Heating
5: polyphosphoric acid / 1 h / 90 - 100 °C
View Scheme
参考文献
Cagniant,P. et al.
Bulletin de la Societe Chimique de France, 1969 , p. 985 - 991
反应条件
1: 150 °C
2: (i) LiAlH4, Et2O (ii) HBr, H2SO4, AcOH
3: aq. ethanol
4: K2CO3 / aq. ethanol / 48 h / Heating
5: polyphosphoric acid / 1 h / 90 - 100 °C
View Scheme
参考文献
Cagniant,P. et al.
Bulletin de la Societe Chimique de France, 1969 , p. 985 - 991
反应条件
1: (hydrolysis)
2: 150 °C
3: (i) LiAlH4, Et2O (ii) HBr, H2SO4, AcOH
4: aq. ethanol
5: K2CO3 / aq. ethanol / 48 h / Heating
6: polyphosphoric acid / 1 h / 90 - 100 °C
View Scheme
参考文献
Cagniant,P. et al.
Bulletin de la Societe Chimique de France, 1969 , p. 985 - 991
反应条件
1: (hydrolysis)
2: 150 °C
3: (i) LiAlH4, Et2O (ii) HBr, H2SO4, AcOH
4: aq. ethanol
5: K2CO3 / aq. ethanol / 48 h / Heating
6: polyphosphoric acid / 1 h / 90 - 100 °C
View Scheme
参考文献
Cagniant,P. et al.
Bulletin de la Societe Chimique de France, 1969 , p. 985 - 991
反应条件
1: hydrogen bromide; water / acetic acid / 2 h / |Inert atmosphere; |Reflux
2: pyridine / dichloromethane / 0 - 20 °C / |Inert atmosphere
3: lithium chloride; bis-triphenylphosphine-palladium(II) chloride; 2,6-di-tert-butyl-4-methyl-phenol / N,N-dimethyl-formamide / 18 h / 90 °C / |Inert atmosphere
View Scheme
参考文献
Romanov-Michailidis, Fedor; Guenee, Laure; Alexakis, Alexandre
Angewandte Chemie - International Edition, 2013 , vol. 52, # 35 p. 9266 - 9270
Angew. Chem., 2013 , vol. 125, # 35 p. 9436 - 9440
反应条件
1: pyridine / dichloromethane / 0 - 20 °C / |Inert atmosphere
2: lithium chloride; bis-triphenylphosphine-palladium(II) chloride; 2,6-di-tert-butyl-4-methyl-phenol / N,N-dimethyl-formamide / 18 h / 90 °C / |Inert atmosphere
View Scheme
参考文献
Romanov-Michailidis, Fedor; Guenee, Laure; Alexakis, Alexandre
Angewandte Chemie - International Edition, 2013 , vol. 52, # 35 p. 9266 - 9270
Angew. Chem., 2013 , vol. 125, # 35 p. 9436 - 9440
