3,4-二氢化-5-甲基-1(2H)-萘酮合成路线 （共 40 条）
反应条件
1: diethyl ether / Erhitzen des Reaktionsprodukts mit Palladium/Kohle bis auf 270grad 2: dibenzoyl peroxide; CCl4; N-bromo-succinimide / unter Einwirkung von UV-Licht View Scheme
参考文献
Marvel; Wilson
Journal of Organic Chemistry, 1958 , vol. 23, p. 1483,1486
参考文献
Tettweiler; Drishaus
Justus Liebigs Annalen der Chemie, 1935 , vol. 520, p. 163,180
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Mercer; Robertson; Cahn
Journal of the Chemical Society, 1935 , p. 997,999
参考文献
Morin,F.G.; Horton,W.J.; Grant,D.M.
Journal of the American Chemical Society, 1983 , vol. 105, p. 3992
反应条件
tin(IV) chloride; benzene
参考文献
Newman et al.
Journal of the American Chemical Society, 1953 , vol. 75, p. 347
反应条件
bis-triphenylphosphine-palladium(II) chloride; 2,6-di-tert-butyl-4-methyl-phenol; lithium chloride in N,N-dimethyl-formamide
T=90°C; 18 h; Inert atmosphere;
参考文献
Romanov-Michailidis, Fedor; Guenee, Laure; Alexakis, Alexandre
Angewandte Chemie - International Edition, 2013 , vol. 52, # 35 p. 9266 - 9270
Angew. Chem., 2013 , vol. 125, # 35 p. 9436 - 9440
反应条件
bis-triphenylphosphine-palladium(II) chloride; 2,6-di-tert-butyl-4-methyl-phenol; lithium chloride in N,N-dimethyl-formamide
T=90°C; 18 h; Inert atmosphere;
参考文献
Romanov-Michailidis, Fedor; Guenee, Laure; Alexakis, Alexandre
Angewandte Chemie - International Edition, 2013 , vol. 52, # 35 p. 9266 - 9270
Angew. Chem., 2013 , vol. 125, # 35 p. 9436 - 9440
反应条件
1: 52 percent / NaH / tetrahydrofuran; dimethylsulfoxide / Ambient temperature
2: 94 percent / H2 / 10percent Pd/C / ethanol / 1551.4 Torr
3: PCl5 / benzene / 1 h
4: SnCl4 / benzene / 0.25 h / 0 °C
View Scheme
参考文献
Zhang, Xiaoyan; De Los Angeles, Joseph E.; He, Mei-Ying; Dalton, James T.; Shams, Gamal; Lei, Longping; Patil, Popat N.; Feller, Dennis R.; Miller, Duane D.; Hsu, Fu-Lian
Journal of Medicinal Chemistry, 1997 , vol. 40, # 19 p. 3014 - 3024
反应条件
1: 94 percent / H2 / 10percent Pd/C / ethanol / 1551.4 Torr
2: PCl5 / benzene / 1 h
3: SnCl4 / benzene / 0.25 h / 0 °C
View Scheme
参考文献
Zhang, Xiaoyan; De Los Angeles, Joseph E.; He, Mei-Ying; Dalton, James T.; Shams, Gamal; Lei, Longping; Patil, Popat N.; Feller, Dennis R.; Miller, Duane D.; Hsu, Fu-Lian
Journal of Medicinal Chemistry, 1997 , vol. 40, # 19 p. 3014 - 3024
反应条件
acetic anhydride
T=250°C; P=18 Torr; Erhitzen des Reaktionsprodukts unter 25 Torr auf 260grad sowie durch Erhitzen des Calcium-Salzes;
参考文献
Tettweiler; Drishaus
Justus Liebigs Annalen der Chemie, 1935 , vol. 520, p. 163,180
反应条件
pyridine; chromium(VI) oxide in dichloromethane
参考文献
Demole,E.; Enggist,P.
Helvetica Chimica Acta, 1978 , vol. 61, p. 1335 - 1341
