反应条件
1.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -73 °C
1.2: N,N'-dimethyl-N,N'-propylene urea / tetrahydrofuran; hexane / 17.5 h / 20 °C
2.1: 40.3 g / TsOH*H2O / dioxane; methanol / 4.5 h / 20 °C
3.1: 75 percent / Li; 1,3-diaminopropane; KO-t-Bu / 24 h / 40 - 45 °C
View Scheme
参考文献
Godt, Adelheid; Duda, Stefan; Uensal, Oemer; Thiel, Juergen; Haerter, Alice; Roos, Mark; Tschierske, Carsten; Diele, Siegmar
Chemistry - A European Journal, 2002 , vol. 8, # 22 p. 5094 - 5106
