反应条件
1: 69.3 percent / butylene oxide / 12 h / 65 °C
2: 89 percent / lithium aluminum hydride / tetrahydrofuran; diethyl ether / 0 - 5 °C
3: 1.) sodium hydride / 1.) DMF, rt, 1h; 2.) rt, 2 h
View Scheme
参考文献
Loeliger; Bollag; Mayer
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 1 p. 9 - 15
