乙酰氧基-(4-氯磺酰基苯基)乙酸甲酯合成路线 （共 4 条）
反应条件
1: NH3 2: aqueous ethanol.H2SO4 View Scheme
参考文献
Sytschewa; Schtschukina
Sb. Statei Obshch. Khim., 1953 , p. 527,529
Chem.Abstr., 1955 , p. 932
Full Text Show Details
Sekikawa; Kakimoto
Nippon Kagaku Zasshi, 1952 , vol. 73, p. 587
Chem.Abstr., 1954 , p. 1985
反应条件
chromium(VI) oxide; sulfuric acid; acetic acid
cooling;
参考文献
Flentge, Charles A.; Chen, Hui-Ju; DeGoey, David A.; Flosi, William J.; Grampovnik, David J.; Huang, Peggy P.; Kempf, Dale J.; Klein, Larry L.; Krueger, Allan C.; Madigan, Darold L.; Randolph, John T.; Sun, Minghua; Yeung, Ming C.; Zhao, Chen
Patent: US2005/131042 A1, 2005 ;
Location in patent: Page/Page column 64 ;
反应条件
sulfuric acid; chromium(VI) oxide in acetic acid
T=0 - 10°C; 0.5 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2004/69793 A2, 2004 ;
Location in patent: Page 75 - 76 ;
WO 2004/069793 A2
反应条件
chromium(VI) oxide; sulfuric acid
T=0°C; 0.583333 h; Product distribution / selectivity;
参考文献
IRONWOOD PHARMACEUTICALS, INC.; JIA, James; MERMERIAN, Ara; KIM, Charles; LUNDRIGAN, Regina; MOORE, Joel
Patent: WO2010/39982 A1, 2010 ;
Location in patent: Page/Page column 92 ;
WO 2010/039982 A1
