1,1-环丙烷二甲酸二甲酯合成路线 （共 18 条）
反应条件
potassium carbonate; [bmim]Br in N,N-dimethyl-formamide T=20 - 70°C;
参考文献
Tetrahedron Letters, , vol. 46, # 4 p. 635 - 638
反应条件
water; potassium carbonate; tetra(n-butyl)ammonium hydrogensulfate in benzene T=80°C; 9 h;
参考文献
Synthesis, , # 8 p. 738 - 739
反应条件
potassium carbonate; 18-crown-6 ether in butanone 3 h; Heating;
参考文献
Synthetic Communications, , vol. 26, # 3 p. 525 - 530
反应条件
tetrabutylammomium bromide; potassium carbonate
反应条件
tetrabutylammomium bromide; potassium carbonate
反应条件
N(Et)4ClO4 in N,N-dimethyl-formamide electrolysis;
参考文献
Chemistry Letters, , p. 2235 - 2238
反应条件
sodium hydride 1.) THF, 0 deg C, 10 min, 2.) THF, HMPA, from -70 to 0 deg C, 3.5 h; Yield given. Multistep reaction;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 66, # 7 p. 2042 - 2047
反应条件
lithium aluminium tetrahydride in diethyl ether T=0 - 20°C; 4 h;
参考文献
JANSSEN PHARMACEUTICA, N.V.
Patent: WO2005/30694 A1, 2005 ;
Location in patent: Page/Page column 84-85 ;
WO 2005/030694 A1
反应条件
Wilkinson's catalyst; acetic acid in tetrahydrofuran T=200°C; 4 h;
参考文献
Dzhemilev, U. M.; Khusnutdinov, R. I.; Shchadneva, N. A.; Tolstikov, G. A.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990 , vol. 39, # 7.2 p. 1447 - 1450
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1990 , # 7 p. 1598 - 1601
反应条件
samarium diiodide; iron(III) tris(dibenzoylmethane); tert-butyl alcohol in tetrahydrofuran 0.166667 h; Ambient temperature;
参考文献
Imamoto, Tsuneo; Hatajima, Toshihiko; Yoshizawa, Takeshi
Tetrahedron Letters, 1994 , vol. 35, # 42 p. 7805 - 7808
