4-(羟甲基)苯甲酸甲酯合成路线 （共 132 条）
反应条件
sodium tetrahydroborate; water in tetrahydrofuran 0.0833333 h; Ambient temperature;
参考文献
Nagao, Yoshimitsu; Kawabata, Kohji; Seno, Kaoru; Fujita, Eiichi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2470 - 2473
反应条件
1: 58 percent Spectr. / iodosylbenzene; 1,1,1,3,3,3-hexafluoro-2-propanol; aq. HBF4 / CH2Cl2 / 4 h / 20 °C 2: NaBH4 / methanol / 1 h / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 129, # 10 p. 2772 - 2773
反应条件
1: 64 percent Spectr. / hydroxy(phenyl)(tetrafluoroborato)-λ3-iodane; 1,1,1,3,3,3-hexafluoro-2-propanol / CH2Cl2; H2O / 5.5 h / 20 °C 2: NaBH4 / methanol / 1 h / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 129, # 10 p. 2772 - 2773
反应条件
water; hydrazine hydrate in tetrahydrofuran; methanol T=60°C;
参考文献
Russian Journal of Organic Chemistry, , vol. 49, # 2 p. 212 - 220
Zh. Org. Khim., , vol. 49, # 2 p. 223 - 231,9
反应条件
1: T=25°C; 0.166667 h; 2: With sodium tetrahydroborate; boric acid T=25°C; 0.5 h;
参考文献
Byung, Tae Cho; Sang, Kyu Kang
Tetrahedron, 2005 , vol. 61, # 24 p. 5725 - 5734
反应条件
copper(II) bis(trifluoromethanesulfonate) T=20°C; 16 h;
参考文献
Broehmer, Manuel C.; Mundinger, Stephan; Braese, Stefan; Bannwarth, Willi
Angewandte Chemie - International Edition, 2011 , vol. 50, # 27 p. 6175 - 6177
反应条件
hydrogenchloride; samarium in tetrahydrofuran T=20°C; Title compound not separated from byproducts;
参考文献
Talukdar; Fang
Journal of Organic Chemistry, 2001 , vol. 66, # 1 p. 330 - 333
反应条件
ammonium hydroxide; titanium(III) chloride in methanol T=20 - 25°C; pH=10 - 11; 0.0833333 h;
参考文献
European Journal of Organic Chemistry, , # 19 p. 3326 - 3335
反应条件
1: 1-methyl-piperazine With formic acid 0.25 h; cooling; 2: 4-formylbenzoic acid methyl ester T=180 - 200°C; Leuckart-Wallach reaction; 8 h; Further stages.;
参考文献
Ignatovich; Gusak; Chernikhova; Kozlov; Koroleva
Chemistry of Heterocyclic Compounds, 2007 , vol. 43, # 12 p. 1540 - 1543
反应条件
glucose dehydrogenase; β-D-glucopyranose; beta-nicotinamide adeninedinucleotide phosphatedisodium salt; catalase from Micrococcus lysodeikticus; cytochrome P450 BM3 monooxygenase from Bacillus megaterium F87A, L188C double mutant; potassium chloride; oxygen; tris(hydroxymethyl)methylamine hydrochloride in aq. phosphate buffer; dimethyl sulfoxide T=30°C; pH=7.5; 24 h; Green chemistryEnzymatic reaction; Reagent/catalyst; regioselective reaction;
参考文献
Green Chemistry, , vol. 15, # 9 p. 2408 - 2421
