2-氟-5-(三氟甲基)吡啶合成路线 (共 6 条)
反应条件
2,4,6-trimethyl-pyridine; hydrogen fluoride T=120°C; 1 h;
参考文献
Chemistry Letters, , # 3 p. 509 - 512
反应条件
indium; [N-butylthiazolium][Br] T=95°C; 14 h; Green chemistry;
参考文献
Molecules, , vol. 18, # 1 p. 398 - 407
参考文献
European Journal of Medicinal Chemistry, , vol. 24, # 3 p. 249 - 258
反应条件
acetic acid in tetrahydrofuran; hexane; water
参考文献
DowElanco
Patent: US5324837 A1, 1994 ;
反应条件
sodium hydride in dimethyl sulfoxide Inert atmosphere;
参考文献
Renga, James M.; McLaren, Kevin L.; Ricks, Michael J.
Organic Process Research and Development, 2003 , vol. 7, # 3 p. 267 - 271