3-(4,4-二甲基-4,5-二氢-1,3-氧唑-2-基)吡啶合成路线 （共 33 条）
反应条件
tetrachloromethane; triethylamine; triphenylphosphine in pyridine; acetonitrile Ambient temperature;
参考文献
Vorbruggen; Krolikiewicz
Tetrahedron, 1993 , vol. 49, # 41 p. 9353 - 9372
反应条件
Kaolinitic clay T=165°C; 24 h;
参考文献
Jnaneshwara; Deshpande; Lalithambika; Ravindranathan; Bedekar
Tetrahedron Letters, 1998 , vol. 39, # 5-6 p. 459 - 462
反应条件
1: BuLi / diethyl ether / -78 °C 2: 1) trimethyltin chloride (Me3SnCl) / 2) (Ph3P)4Pd <tetrakis(triphenylphosphine)palladium(O)> / 1) in Et2O, -78 deg C, 2) C6H6, 24h, reflux View Scheme
参考文献
Tetrahedron Letters, , vol. 27, # 43 p. 5269 - 5270
反应条件
trimethylstannyl chloride; tetrakis(triphenylphosphine) palladium(0) 1) in Et2O, -78 deg C, 2) C6H6, 24h, reflux; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 27, # 43 p. 5269 - 5270
参考文献
Hauck, Albert E.; Giam, Choo-Seng
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2070 - 2076
反应条件
1: thionyl chloride / 24 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 47, # 13 p. 2633 - 2637
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in benzene 0.5 h; Ambient temperatureother reagents, solvents, time; Product distribution;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2070 - 2076
反应条件
Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 47, # 13 p. 2633 - 2637
反应条件
Yield given. Multistep reaction;
参考文献
Synthesis, , # 8 p. 693 - 696
反应条件
1: 2.) S / 1.) THF, ether, a) -78 deg C, 1 h, b) RT, 1 h, 2.) toluene, reflux, 2 h 2: 72 percent / conc. aq. HCl / 18 h / Heating 3: SOCl2 / 2 h / Heating 4: CH2Cl2 / Ambient temperature View Scheme
参考文献
Moos; Bergmeier; Coughenour; Davis; Hershenson; Kester; McKee; Marriott; Schwarz; Tecle; Thomas
Journal of Pharmaceutical Sciences, 1992 , vol. 81, # 10 p. 1015 - 1019
