7,8-二氢-[1,3]二氧代[4,5-g]异喹啉合成路线 （共 18 条）
反应条件
trichlorophosphate in acetonitrile
T=0°C; 4 h;
参考文献
Soriano, Maria Del Pilar C.; Shankaraiah, Nagula; Santos, Leonardo Silva
Tetrahedron Letters, 2010 , vol. 51, # 13 p. 1770 - 1773
反应条件
iodosylbenzene; tetra-(n-butyl)ammonium iodide in acetonitrile
T=0°C; 0.25 h;
参考文献
Huang, Wei-Jan; Singh, Om V.; Chen, Chung-Hsiung; Chiou, Sheng-You; Lee, Shoei-Sheng
Helvetica Chimica Acta, 2002 , vol. 85, # 4 p. 1069 - 1078
反应条件
1: 5 h / 160 °C
2: polyphosphoric acid (PPA) / 4 h / 150 °C
View Scheme
参考文献
Caroon, Joan M.; Clark, Robin D.; Kluge, Arthur F.; Lee, Chi-Ho; Strosberg, Arthur M.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1426 - 1433
反应条件
1: ammonium acetate / acetic acid / 6 h / Heating
2: 72 percent / LiAlH4 / tetrahydrofuran / 8 h / Heating
3: 87 percent / 20 h / Heating
4: 42 percent
View Scheme
参考文献
Marsden, Richard; MacLean, David B.
Canadian Journal of Chemistry, 1984 , vol. 62, p. 1392 - 1399
反应条件
1: 72 percent / LiAlH4 / tetrahydrofuran / 8 h / Heating
2: 87 percent / 20 h / Heating
3: 42 percent
View Scheme
参考文献
Marsden, Richard; MacLean, David B.
Canadian Journal of Chemistry, 1984 , vol. 62, p. 1392 - 1399
反应条件
1: 91 percent / trimethylsilyl azide / 1,3,5-trimethyl-benzene / 40 h / Heating
2: 75 percent / diisobutylaluminium hydride / diethyl ether; hexane / -78 deg C --> 0 deg C, 4 h
3: 46 percent / phosphorus oxychloride / acetonitrile / 2 h / Heating
View Scheme
参考文献
Slemon, Clarke E.; Hellwig, Louise C.; Ruder, Jean-Pierre; Hoskins, Eric W.; MacLean, David B.
Canadian Journal of Chemistry, 1981 , vol. 59, p. 3055 - 3060
反应条件
1: 86 percent / thionyl chloride / 1 h / Heating
2: 91 percent / trimethylsilyl azide / 1,3,5-trimethyl-benzene / 40 h / Heating
3: 75 percent / diisobutylaluminium hydride / diethyl ether; hexane / -78 deg C --> 0 deg C, 4 h
4: 46 percent / phosphorus oxychloride / acetonitrile / 2 h / Heating
View Scheme
参考文献
Slemon, Clarke E.; Hellwig, Louise C.; Ruder, Jean-Pierre; Hoskins, Eric W.; MacLean, David B.
Canadian Journal of Chemistry, 1981 , vol. 59, p. 3055 - 3060
反应条件
1: 75 percent / diisobutylaluminium hydride / diethyl ether; hexane / -78 deg C --> 0 deg C, 4 h
2: 46 percent / phosphorus oxychloride / acetonitrile / 2 h / Heating
View Scheme
参考文献
Slemon, Clarke E.; Hellwig, Louise C.; Ruder, Jean-Pierre; Hoskins, Eric W.; MacLean, David B.
Canadian Journal of Chemistry, 1981 , vol. 59, p. 3055 - 3060
反应条件
toluene; trichlorophosphate
参考文献
Dey; Govindachari
Proceedings of the National Institute of Sciences of India, 1940 , vol. 6, p. 219,221
参考文献
Decker; Kropp; Hoyer; Becker
Justus Liebigs Annalen der Chemie, 1913 , vol. 395, p. 313
Full Text Show Details
Decker
Patent: DE245095 ;
Full Text Show Details
Decker
Patent: DE234850 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 10, p. 1186,1188
