3,5-二氯苯硼酸频那醇酯合成路线 (共 15 条)
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium hydroxide in tert-butyl methyl ether; water T=80°C; Suzuki-Miyaura coupling; 3 h;
参考文献
Harrisson, Peter; Morris, James; Steel, Patrick G.; Marder, Todd B.
Synlett, 2009 , # 1 p. 147 - 150
反应条件
copper(l) iodide; 1,10-phenanthroline; potassium iodide in methanol; water T=80°C; 1 h; High pressure;
参考文献
Partridge, Benjamin M.; Hartwig, John F.
Organic Letters, 2013 , vol. 15, # 1 p. 140 - 143
反应条件
Oxonereg;; sodium hydroxide; sodium hydrogencarbonate in water; acetone T=0°C; 0.283333 - 0.333333 h;
参考文献
Board of Trustees of Michigan State University
Patent: US2004/30197 A1, 2004 ;
Location in patent: Page 19-21 ;
反应条件
1: With sodium periodate in tetrahydrofuran; water 0.25 h; 2: With hydrogenchloride in tetrahydrofuran; water 4 h;
参考文献
Murphy, Jaclyn M.; Tzschucke, C. Christoph; Hartwig, John F.
Organic Letters, 2007 , vol. 9, # 5 p. 757 - 760
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium hydroxide in tetrahydrofuran; ethylene glycol dimethyl ether; water
T=75°C; Suzuki Coupling;
参考文献
Lahm, George P.; Cordova, Daniel; Barry, James D.; Pahutski, Thomas F.; Smith, Ben K.; Long, Jeffrey K.; Benner, Eric A.; Holyoke, Caleb W.; Joraski, Kathleen; Xu, Ming; Schroeder, Mark E.; Wagerle, Ty; Mahaffey, Michael J.; Smith, Rejane M.; Tong, My-Hahn
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 10 p. 3001 - 3006