1-甲基-6-硝基-1H-吲唑合成路线 （共 16 条）
反应条件
1: 6-nitro-1H-indazole With sodium hydride in N,N-dimethyl-formamide T=20°C; 0.333333 h; 2: methyl iodide in N,N-dimethyl-formamide
参考文献
The United States of America, as represented by the Secretary, Department of Health and Human Services; Science Applications International Corporation (SAIC); Albany Molecular Research, Inc.
Patent: WO2009/42907 A1, 2009 ;
Location in patent: Page/Page column 84 ;
WO 2009/042907 A1
反应条件
sodium hydride in N,N-dimethyl-formamide T=0 - 20°C; 1 h;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 21, # 13 p. 3821 - 3830
反应条件
potassium hydroxide in water T=45°C;
参考文献
Journal of Chemical Research, Miniprint, , # 11 p. 2601 - 2615
反应条件
trifluorormethanesulfonic acid in dichloromethane Inert atmosphere; Reagent/catalystSolvent; regioselective reaction;
参考文献
Baddam, Sudhakar Reddy; Uday Kumar; Panasa Reddy; Bandichhor, Rakeshwar
Tetrahedron Letters, 2013 , vol. 54, # 13 p. 1661 - 1663
反应条件
boron trifluoride diethyl etherate T=70°C; 6 h; Inert atmosphere; regioselective reaction;
参考文献
Baddam, Sudhakar Reddy; Uday Kumar; Panasa Reddy; Bandichhor, Rakeshwar
Tetrahedron Letters, 2013 , vol. 54, # 13 p. 1661 - 1663
反应条件
trifluorormethanesulfonic acid in dichloromethane Inert atmosphere; regioselective reaction;
参考文献
Tetrahedron Letters, , vol. 54, # 13 p. 1661 - 1663
反应条件
1: glacial acetic acid / 10 °C / Diazotization 2: diluted NaOH-solution View Scheme
参考文献
Chemische Berichte, , vol. 53, p. 1213,1216, 1227
参考文献
Justus Liebigs Annalen der Chemie, , vol. 451, p. 285,302
参考文献
Justus Liebigs Annalen der Chemie, , vol. 451, p. 285,302
Chemische Berichte, , vol. 53, p. 1213,1216, 1227
参考文献
Justus Liebigs Annalen der Chemie, , vol. 451, p. 285,302
Chemische Berichte, , vol. 53, p. 1213,1216, 1227
