N-(苄氧基羰基)-1,2,3,4-四氢吡啶合成路线 （共 25 条）
反应条件
1: 76 percent / NaBH4 / methanol / -80 °C
2: NaBH4, CeCl3 / methanol / 0 °C
View Scheme
参考文献
Yamada, Hironari; Aoyagi, Sakae; Kibayashi, Chihiro
Tetrahedron Letters, 1996 , vol. 37, # 48 p. 8787 - 8790
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere
1.2: 4 h / -78 °C / Inert atmosphere
2.1: sodium tetrahydroborate / methanol / 0.25 h / 0 °C / Inert atmosphere
3.1: sulfuric acid / tetrahydrofuran / 1 h / Inert atmosphere
View Scheme
参考文献
De Simone, Filippo; Saget, Tanguy; Benfatti, Fides; Almeida, Sofia; Waser, Jerome
Chemistry - A European Journal, 2011 , vol. 17, # 51 p. 14527 - 14538
反应条件
1: 91 percent / Et4NOTs / Electrochemical reaction
2: 92 percent / NH4Cl / Heating
View Scheme
参考文献
Furukubo, Shigeru; Moriyama, Noriaki; Onomura, Osamu; Matsumura, Yoshihiro
Tetrahedron Letters, 2004 , vol. 45, # 44 p. 8177 - 8181
反应条件
1: 84 percent / Oxone(R); aq. K2CO3 / acetone / 2 h / 20 °C
2: 76 percent / acetonitrile / 1 h / Heating
View Scheme
参考文献
Takeuchi, Yasuo; Oshige, Miyo; Azuma, Kumiko; Abe, Hitoshi; Harayama, Takashi
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 7 p. 868 - 869
反应条件
1: 76 percent / oxone(R); K2CO3 / H2O; acetone / 2 h / 20 °C
2: 88 percent / DMAP; Et3N / 2 h / 20 °C
View Scheme
参考文献
Takeuchi, Yasuo; Azuma, Kumiko; Abe, Hitoshi; Sasaki, Kenji; Harayama, Takashi
Chemical and pharmaceutical bulletin, 2002 , vol. 50, # 7 p. 1011 - 1012
