9-异亚丙基-1,4-二甲氧基-苯并降冰片烯合成路线 （共 8 条）
反应条件
in tetrahydrofuran; hexane
1.) 0 deg C, 1 h, 2.) reflux, 16 h;
参考文献
Paquette, Leo A.; Hertel, Larry W.; Gleiter, Rolf; Boehm, Michael C.; Beno, Mark A.; Christoph, Gary G.
Journal of the American Chemical Society, 1981 , vol. 103, # 24 p. 7106 - 7121
反应条件
1: KO-tert-Bu
2: 70 percent / lithium, tert-butanol / tetrahydrofuran / 15 h / Heating
3: 90 percent / 6 N hydrochloric acid / diethyl ether / 12 h / Ambient temperature
4: 65 percent / tetrahydrofuran; hexane / 1.) 0 deg C, 1 h, 2.) reflux, 16 h
View Scheme
参考文献
Paquette, Leo A.; Hertel, Larry W.; Gleiter, Rolf; Boehm, Michael C.; Beno, Mark A.; Christoph, Gary G.
Journal of the American Chemical Society, 1981 , vol. 103, # 24 p. 7106 - 7121
反应条件
1: 90 percent / 6 N hydrochloric acid / diethyl ether / 12 h / Ambient temperature
2: 65 percent / tetrahydrofuran; hexane / 1.) 0 deg C, 1 h, 2.) reflux, 16 h
View Scheme
参考文献
Paquette, Leo A.; Hertel, Larry W.; Gleiter, Rolf; Boehm, Michael C.; Beno, Mark A.; Christoph, Gary G.
Journal of the American Chemical Society, 1981 , vol. 103, # 24 p. 7106 - 7121
反应条件
1: 70 percent / lithium, tert-butanol / tetrahydrofuran / 15 h / Heating
2: 90 percent / 6 N hydrochloric acid / diethyl ether / 12 h / Ambient temperature
3: 65 percent / tetrahydrofuran; hexane / 1.) 0 deg C, 1 h, 2.) reflux, 16 h
View Scheme
参考文献
Paquette, Leo A.; Hertel, Larry W.; Gleiter, Rolf; Boehm, Michael C.; Beno, Mark A.; Christoph, Gary G.
Journal of the American Chemical Society, 1981 , vol. 103, # 24 p. 7106 - 7121
反应条件
hydrogen; Wilkinson's catalyst in benzene
参考文献
Buttrus, Nabeel H.; Cornforth, Sir John; Hitchcock, Peter B.; Kumar, Ashok; Stuart, Alan S.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 851 - 858
反应条件
1: 4.89 g / diethyl ether / 168 h
2: 7.2 g / sodium methoxide / methanol / 2 h / 70 °C
3: 300 mg / H2 / tris(triphenylphosphine)rhodium chloride / benzene
View Scheme
参考文献
Buttrus, Nabeel H.; Cornforth, Sir John; Hitchcock, Peter B.; Kumar, Ashok; Stuart, Alan S.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 851 - 858
反应条件
1: 71.5 percent / sodium ethoxide / ethanol / 1 h / Ambient temperature
2: 4.89 g / diethyl ether / 168 h
3: 7.2 g / sodium methoxide / methanol / 2 h / 70 °C
4: 300 mg / H2 / tris(triphenylphosphine)rhodium chloride / benzene
View Scheme
参考文献
Buttrus, Nabeel H.; Cornforth, Sir John; Hitchcock, Peter B.; Kumar, Ashok; Stuart, Alan S.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 851 - 858
反应条件
1: 7.2 g / sodium methoxide / methanol / 2 h / 70 °C
2: 300 mg / H2 / tris(triphenylphosphine)rhodium chloride / benzene
View Scheme
参考文献
Buttrus, Nabeel H.; Cornforth, Sir John; Hitchcock, Peter B.; Kumar, Ashok; Stuart, Alan S.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 851 - 858
