4-(4-甲氧基苯基)丁基氯合成路线 （共 13 条）
反应条件
phosphorus pentachloride
参考文献
Diss. <Tieraerztl. Hochsch. Berlin 1924> S. 20
反应条件
ammonium hydroxide T=0°C; 0.5 h; Yield given;
参考文献
Perez-Medrano, Arturo; Donnelly-Roberts, Diana L.; Honore, Prisca; Hsieh, Gin C.; Namovic, Marian T.; Peddi, Sridhar; Shuai, Qi; Wang, Ying; Faltynek, Connie R.; Jarvis, Michael F.; Carroll, William A.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 10 p. 3366 - 3376
反应条件
1: AlCl3; tetrachloroethane / -5 °C 2: diethyl ether / Erhitzen des nach der Hydrolyse erhaltenen Reaktionsprodukts unter vermindertem Druck auf 120-160grad 3: selenium / 220 - 330 °C 4: aqueous HBr; glacial acetic acid View Scheme
参考文献
Haworth; Sheldrick
Journal of the Chemical Society, 1934 , p. 1950
反应条件
1: AlCl3; tetrachloroethane / -5 °C 2: diethyl ether / Erhitzen des nach der Hydrolyse erhaltenen Reaktionsprodukts unter vermindertem Druck auf 120-160grad View Scheme
参考文献
Haworth; Sheldrick
Journal of the Chemical Society, 1934 , p. 1950
反应条件
unter vermindertem Druck;
参考文献
Krollpfeiffer; Schaefer
Chemische Berichte, 1923 , vol. 56, p. 630
反应条件
1: aq. ammonia / 0.5 h / 0 °C 2: 14 percent / LiAlH4 / CH2Cl2; tetrahydrofuran / 96 h / Heating View Scheme
参考文献
Ganellin, C. Robin; Leurquin, Fabien; Piripitsi, Antonia; Arrang, Jean-Michel; Garbarg, Monique; Ligneau, Xavier; Schunack, Walter; Schwartz, Jean-Charles
Archiv der Pharmazie, 1998 , vol. 331, # 12 p. 395 - 404
反应条件
1: SnCl4; benzene 2: copper oxide-chromium oxide / 125 - 200 °C / 154457 Torr / Hydrogenolyse 3: CrO3; water containing acetic acid; propionic acid View Scheme
参考文献
Thomas; Nathan
Journal of the American Chemical Society, 1948 , vol. 70, p. 331,333
反应条件
1: SnCl4; benzene 2: copper oxide-chromium oxide / 125 - 200 °C / 154457 Torr / Hydrogenation View Scheme
参考文献
Thomas; Nathan
Journal of the American Chemical Society, 1948 , vol. 70, p. 331,333
反应条件
1: SnCl4; benzene 2: copper oxide-chromium oxide / 125 - 200 °C / 154457 Torr / Hydrogenolyse View Scheme
参考文献
Thomas; Nathan
Journal of the American Chemical Society, 1948 , vol. 70, p. 331,333
反应条件
aluminium trichloride in 1,2-dichloro-ethane
0.0833333 h;
参考文献
Kogan, Timothy P.; Dupre, Brian; Bui, Huong; McAbee, Kathy L.; Kassir, Jamal M.; Scott, Ian L.; Hu, Xin; Vanderslice, Peter; Beck, Pamela J.; Dixon, Richard A. F.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 7 p. 1099 - 1111
