1,5 -二苯基- 1H -吡唑合成路线 （共 46 条）
反应条件
1: concd. H2SO4 / ethanol; H2O / 1 h / Heating
2: 33percent NaOH
3: 1 h / 250 °C
View Scheme
参考文献
Begtrup, Mikael; Vedso, Per; Cabildo, Pilar; Claramunt, Rosa Maria; Elguero, Jose; Meutermans, Wim
Magnetic Resonance in Chemistry, 1992 , vol. 30, # 5 p. 455 - 459
反应条件
1: concd. H2SO4 / ethanol; H2O / 1 h / Heating
2: 33percent NaOH
3: 1 h / 250 °C
View Scheme
参考文献
Begtrup, Mikael; Vedso, Per; Cabildo, Pilar; Claramunt, Rosa Maria; Elguero, Jose; Meutermans, Wim
Magnetic Resonance in Chemistry, 1992 , vol. 30, # 5 p. 455 - 459
反应条件
1: 100 percent / KOH / ethanol / 5 h / Heating
2: 96 percent / 26 h / 210 °C
View Scheme
参考文献
Menozzi; Mosti; Schenone
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 6 p. 1669 - 1675
反应条件
1: 83 percent / ethanol / 2 h / Heating
2: 100 percent / KOH / ethanol / 5 h / Heating
3: 96 percent / 26 h / 210 °C
View Scheme
参考文献
Menozzi; Mosti; Schenone
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 6 p. 1669 - 1675
反应条件
1: 94 percent / 1 h / Heating
2: 83 percent / ethanol / 2 h / Heating
3: 100 percent / KOH / ethanol / 5 h / Heating
4: 96 percent / 26 h / 210 °C
View Scheme
参考文献
Menozzi; Mosti; Schenone
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 6 p. 1669 - 1675
反应条件
diphosphorus pentasulfide
T=220°C;
参考文献
Knorr; Duden
Chemische Berichte, 1893 , vol. 26, p. 112
反应条件
1: 5 h / 80 °C / Inert atmosphere; Neat (no solvent)
2: iodine / dichloromethane / 3 h / 40 °C / Inert atmosphere
View Scheme
参考文献
Zora, Metin; Kivrak, Arif; Yazici, Ceyda
Journal of Organic Chemistry, 2011 , vol. 76, # 16 p. 6726 - 6742
反应条件
1.1: n-butyllithium / tetrahydrofuran / -40 °C
1.2: -40 - 0 °C
1.3: 5 °C
2.1: 5 h / 80 °C / Inert atmosphere; Neat (no solvent)
3.1: iodine / dichloromethane / 3 h / 40 °C / Inert atmosphere
View Scheme
参考文献
Zora, Metin; Kivrak, Arif; Yazici, Ceyda
Journal of Organic Chemistry, 2011 , vol. 76, # 16 p. 6726 - 6742
反应条件
T=600°C; P=0.003 - 0.01 Torr; 0.666667 h; Further byproducts given. Title compound not separated from byproducts;
参考文献
Hickson, Clare L.; McNab, Hamish
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1569 - 1572
反应条件
1: sodium wire; diethyl ether / man saugt ab, loest in Wasser, ueberschichtet mit Aether und zersetzt mit Essigsaeure
2: diethyl ether / bei der Destillation
View Scheme
参考文献
v. Auwers; Schmidt
Chemische Berichte, 1925 , vol. 58, p. 537
