7-羟基-5-甲基-1-茚酮合成路线 （共 21 条）
反应条件
1: 85 percent / AlCl3 / 0.5 h / 100 °C
2: 13 percent / AlCl3, NaCl / 0.5 h / 160 °C
3: 96 percent / H2, sodium acetate / 5percent Pd/C / acetic acid / 2 h
View Scheme
参考文献
Muckensturm, Bernard; Diyani, Fouzia
Journal of Chemical Research, Miniprint, 1995 , # 11 p. 2544 - 2556
反应条件
1: 86 percent / polyphosphonic acid / 0.17 h / 80 - 90 °C
2: 96 percent / H2, sodium acetate / 5percent Pd/C / acetic acid / 2 h
View Scheme
参考文献
Muckensturm, Bernard; Diyani, Fouzia
Journal of Chemical Research, Miniprint, 1995 , # 11 p. 2544 - 2556
反应条件
1: 83 percent / mercuric oxide, HClO4 / 1,2-dimethoxy-ethane / Heating
2: TsOH, nitrooxide / CH2Cl2 / 1 h / 0 °C
3: 90 percent / piperidine, pyridine / 0.17 h / 100 °C
4: 100 percent / H2 / PtO2 / methanol / 3 h
5: 86 percent / polyphosphonic acid / 0.17 h / 80 - 90 °C
6: 96 percent / H2, sodium acetate / 5percent Pd/C / acetic acid / 2 h
View Scheme
参考文献
Muckensturm, Bernard; Diyani, Fouzia
Journal of Chemical Research, Miniprint, 1995 , # 11 p. 2544 - 2556
反应条件
1: With AlCl3, aluminium chloride
T=90 - 180°C; 5 h; Inert atmosphere;
2: With hydrogenchloride; water
T=0°C; 3 h; Inert atmosphere;
参考文献
Morrison, Christopher F.; Stamp, Craig T.M.; Burnell, D. Jean
Tetrahedron Letters, 2009 , vol. 50, # 50 p. 7021 - 7023
反应条件
1: potassium carbonate / acetone / 24 h / Reflux
2: copper(ll) bromide / chloroform; ethyl acetate / 2 h / 80 °C
3: triethylamine / acetone / 24 h / Reflux
4: anhydrous iron chloride / dichloromethane / 20 °C / Inert atmosphere
5: benzene / Irradiation
View Scheme
参考文献
Sebej, Peter; Lim, Bum Hee; Park, Bong Ser; Givens, Richard S.; Klan, Petr
Organic Letters, 2011 , vol. 13, # 4 p. 644 - 647
反应条件
1: copper(ll) bromide / chloroform; ethyl acetate / 2 h / 80 °C
2: triethylamine / acetone / 24 h / Reflux
3: anhydrous iron chloride / dichloromethane / 20 °C / Inert atmosphere
4: benzene / Irradiation
View Scheme
参考文献
Sebej, Peter; Lim, Bum Hee; Park, Bong Ser; Givens, Richard S.; Klan, Petr
Organic Letters, 2011 , vol. 13, # 4 p. 644 - 647
反应条件
1: triethylamine / acetone / 24 h / Reflux
2: anhydrous iron chloride / dichloromethane / 20 °C / Inert atmosphere
3: benzene / Irradiation
View Scheme
参考文献
Sebej, Peter; Lim, Bum Hee; Park, Bong Ser; Givens, Richard S.; Klan, Petr
Organic Letters, 2011 , vol. 13, # 4 p. 644 - 647
反应条件
1: anhydrous iron chloride / dichloromethane / 20 °C / Inert atmosphere
2: benzene / Irradiation
View Scheme
参考文献
Sebej, Peter; Lim, Bum Hee; Park, Bong Ser; Givens, Richard S.; Klan, Petr
Organic Letters, 2011 , vol. 13, # 4 p. 644 - 647
反应条件
1: AlCl3, aluminium chloride / nitromethane / 15 h / 0 - 50 °C
2: potassium carbonate / acetone / 24 h / Reflux
3: copper(ll) bromide / chloroform; ethyl acetate / 2 h / 80 °C
4: triethylamine / acetone / 24 h / Reflux
5: anhydrous iron chloride / dichloromethane / 20 °C / Inert atmosphere
6: benzene / Irradiation
View Scheme
参考文献
Sebej, Peter; Lim, Bum Hee; Park, Bong Ser; Givens, Richard S.; Klan, Petr
Organic Letters, 2011 , vol. 13, # 4 p. 644 - 647
反应条件
1: triethylamine / dichloromethane / 0 - 20 °C
2: AlCl3, aluminium chloride / nitromethane / 15 h / 0 - 50 °C
3: potassium carbonate / acetone / 24 h / Reflux
4: copper(ll) bromide / chloroform; ethyl acetate / 2 h / 80 °C
5: triethylamine / acetone / 24 h / Reflux
6: anhydrous iron chloride / dichloromethane / 20 °C / Inert atmosphere
7: benzene / Irradiation
View Scheme
参考文献
Sebej, Peter; Lim, Bum Hee; Park, Bong Ser; Givens, Richard S.; Klan, Petr
Organic Letters, 2011 , vol. 13, # 4 p. 644 - 647
