1H-咪唑并(4,5-c)吡啶-4-胺合成路线 （共 4 条）
反应条件
dipotassium hydrogenphosphate in water T=37°C; 72 h; uridine phosphorylase, purine nucleoside phosphorylase;
参考文献
Krenitsky; Rideout; Chao; Koszalka; Gurney; Crouch; Cohn; Wolberg; Vinegar
Journal of Medicinal Chemistry, 1986 , vol. 29, # 1 p. 138 - 143
反应条件
T=37°C; 16 h; alginate gel-entrapped cells of auxotrophic thymine-dependent strain of E. coli, ammonium acetate buffer pH 5.7;
参考文献
Votruba, Ivan; Holy, Antonin; Dvorakova, Hana; Guenter, Jaroslav; Hockova, Dana; et al.
Collection of Czechoslovak Chemical Communications, 1994 , vol. 59, # 10 p. 2303 - 2330
反应条件
4-(N,N-dimethlyamino)pyridine in tetrahydrofuran
T=0 - 20°C; 24 h;
参考文献
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
Patent: WO2007/47793 A2, 2007 ;
Location in patent: Page/Page column 37-38; 90 ;
反应条件
hydrogenchloride; 3-chloro-benzenecarboperoxoic acid in N,N-dimethyl acetamide
T=20°C; 0.416667 h;
参考文献
Seley, Katherine L.; O'Daniel, Peter I.; Salima, Samer
Nucleosides, Nucleotides and Nucleic Acids, 2003 , vol. 22, # 12 p. 2133 - 2144
