N-叔丁氧羰基-1,4-丁二胺合成路线 （共 29 条）
反应条件
in chloroform 1.) 3 h, ice bath, 2.) room temperature, 16 h;
参考文献
Cinelli, Maris A.; Cordero, Brenda; Dexheimer, Thomas S.; Pommier, Yves; Cushman, Mark
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 20 p. 7145 - 7155
反应条件
1: in tetrahydrofuran T=0°C; 18 h; 2: With hydrogenchloride in water pH=6; 3: With sodium hydroxide in water pH=12;
参考文献
HUNTER-FLEMING LIMITED
Patent: WO2005/116050 A1, 2005 ;
Location in patent: Page/Page column 29-30 ;
反应条件
ammonia; hydrogen; nickel in ethanol T=50°C; P=15514.4 Torr; 8 h;
参考文献
Houssin, Raymond; Bernier, Jean-Luc; Henichart, Jean-Pierre
Synthesis, 1988 , # 3 p. 259 - 261
反应条件
sodium hydroxide; hydrogen; nickel in ethanol P=2250.2 Torr; 18 h;
参考文献
Benz, Herbert; Hesse, Manfred
Helvetica Chimica Acta, 1993 , vol. 76, # 4 p. 1636 - 1648
反应条件
formic acid; diisopropyl-carbodiimide in dichloromethane T=20°C; Cooling with ice;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 9 p. 2587 - 2590
反应条件
triphenylphosphine in tetrahydrofuran; water T=0 - 20°C; 23 h;
参考文献
Wakamiya, Tateaki; Yamamoto, Akinori; Kawaguchi, Keita; Kinoshita, Tomohiko; Yamaguchi, Yoshihiro; Itagaki, Yasuhiro; Naoki, Hideo; Nakajima, Terumi
Bulletin of the Chemical Society of Japan, 2001 , vol. 74, # 9 p. 1743 - 1749
反应条件
hydrogen; palladium on activated charcoal in methanol 1 h; Ambient temperature;
参考文献
Arasujo, M. Joso S. M. P.; Ragnarsson, Ulf; Trigo, M. Joaquina S. A. Amaral; Almeida, M. Lurdes S.
Journal of Chemical Research, Miniprint, 1996 , # 8 p. 2143 - 2161
参考文献
Pittelkow, Michael; Lewinsky, Rasmus; Christensen, Jorn Bolstad
Synthesis, 2002 , # 15 p. 2195 - 2202
反应条件
in 1,4-dioxane T=20°C; Inert atmosphere;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 18, # 7 p. 2586 - 2597
反应条件
sodium hydroxide; hydrogen; nickel in ethanol; water T=25°C; P=2068.59 Torr; 20 h; Yield given;
参考文献
Tetrahedron, , vol. 54, # 50 p. 15199 - 15214
