6-氨基-7-羟基-4-甲基香豆素合成路线 （共 11 条）
反应条件
pyridine T=20°C; 24 h;
参考文献
Wiederschain, German Ya.; Kozlova, Inna K.; Ilyina, Galina S.; Mikhaylova, Margarita A.; Beyer, Elena M.
Carbohydrate Research, 1992 , vol. 224, p. 255 - 272
反应条件
sodium dithionite in ammonium hydroxide
0.25 h; Heating;
参考文献
Kozlova, I. K.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1985 , vol. 21, # 7 p. 750 - 753
Khimiya Geterotsiklicheskikh Soedinenii, 1985 , # 7 p. 906 - 909
反应条件
sulfuric acid in water
T=20°C; 24 h;
参考文献
Soares, Ana M.S.; Costa, Susana P.G.; Gonalves, M. Sameiro T.
Tetrahedron, 2010 , vol. 66, # 41 p. 8189 - 8195
反应条件
hydrogenchloride in ethanol
2 h; Heating;
参考文献
Gikas, Evagelos; Parissi-Poulou, Maria; Kazanis, Michael; Vavagianis, Andreas
Synthetic Communications, 2004 , vol. 34, # 22 p. 4233 - 4242
反应条件
1: 100 percent / AlCl3; NaCl / 140 °C
2: 67.6 percent / H2SO4 / H2O / 0 - 5 °C
3: HCl / ethanol / 2 h / Heating
View Scheme
参考文献
Gikas, Evagelos; Parissi-Poulou, Maria; Kazanis, Michael; Vavagianis, Andreas
Synthetic Communications, 2004 , vol. 34, # 22 p. 4233 - 4242
反应条件
1: 67.6 percent / H2SO4 / H2O / 0 - 5 °C
2: HCl / ethanol / 2 h / Heating
View Scheme
参考文献
Gikas, Evagelos; Parissi-Poulou, Maria; Kazanis, Michael; Vavagianis, Andreas
Synthetic Communications, 2004 , vol. 34, # 22 p. 4233 - 4242
反应条件
1: 100 percent / sodium carbonate / H2O; CHCl3
2: 100 percent / AlCl3; NaCl / 140 °C
3: 67.6 percent / H2SO4 / H2O / 0 - 5 °C
4: HCl / ethanol / 2 h / Heating
View Scheme
参考文献
Gikas, Evagelos; Parissi-Poulou, Maria; Kazanis, Michael; Vavagianis, Andreas
Synthetic Communications, 2004 , vol. 34, # 22 p. 4233 - 4242
反应条件
1: 65 percent / nitronium tetrafluoroborate / acetonitrile / 0.5 h / 0 °C
2: 98 percent / Na2S2O4 / aq. NH3 / 0.25 h / Heating
View Scheme
参考文献
Kozlova, I. K.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1985 , vol. 21, # 7 p. 750 - 753
Khimiya Geterotsiklicheskikh Soedinenii, 1985 , # 7 p. 906 - 909
反应条件
1: 90 percent / pyridine / 3 h / 20 °C
2: 1) sodium ethoxide / 1) ethanol, 2) DMSO, oxolane, 20h, reflux
3: sodium methoxide
View Scheme
参考文献
Wiederschain, German Ya.; Kozlova, Inna K.; Ilyina, Galina S.; Mikhaylova, Margarita A.; Beyer, Elena M.
Carbohydrate Research, 1992 , vol. 224, p. 255 - 272
反应条件
pyridine
T=20°C; 3 h;
参考文献
Wiederschain, German Ya.; Kozlova, Inna K.; Ilyina, Galina S.; Mikhaylova, Margarita A.; Beyer, Elena M.
Carbohydrate Research, 1992 , vol. 224, p. 255 - 272
