17Alpha-羟基黄体酮合成路线 （共 90 条）
反应条件
1: With phenyl silane; oxygen; isopropyl alcohol; Mn(dpm)3 in 1,2-dichloro-ethane T=0 - 25°C; 2: With triethyl phosphite in 1,2-dichloro-ethane
参考文献
Magnus; Payne; Waring; Scott; Lynch
Tetrahedron Letters, 2000 , vol. 41, # 50 p. 9725 - 9730
反应条件
in isopropyl alcohol
参考文献
Board of Regents The University of Texas System
Patent: US2002/120170 A1, 2002 ;
参考文献
Livingston, Douglas A.; Petre, Janet E.; Bergh, Carol L.
Journal of the American Chemical Society, 1990 , vol. 112, # 17 p. 6449 - 6450
反应条件
3-chloro-benzenecarboperoxoic acid; RhCl(PPh3)3 in dichloromethane
参考文献
Journal of the American Chemical Society, , vol. 111, # 16 p. 6257 - 6265
反应条件
water; sodium hydroxide in methanol 1 h; Reflux;
参考文献
Bratoeff, Eugene; Garcia, Perla; Heuze, Yvonne; Soriano, Juan; Mejia, Adriana; Labastida, Ana Maria; Valencia, Norma; Cabeza, Marisa
Steroids, 2010 , vol. 75, # 7 p. 499 - 505
反应条件
mercaptoacetic acid in formamide 0.25 h; Ambient temperature;
参考文献
Mikhal'chuk, A. L.; Pschenichnyi, V. N.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 8.1 p. 1479 - 1485
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 8 p. 1686 - 1693
反应条件
water; calcium carbonate; methyl iodide in ethanol 20 h; HeatingInert atmosphere;
参考文献
Claudel, Emilie; Arbez-Gindre, Cecile; Berl, Valerie; Lepoittevin, Jean-Pierre
Synthesis, 2009 , # 20 p. 3391 - 3398
反应条件
rabbit 3-hydroxyhexobarbital dehydrogenase (AKR1C29); NADP in aq. phosphate buffer; ethyl acetate T=37°C; pH=7.4; 0.5 h; Enzymatic reaction; Catalytic behaviorKinetics;
参考文献
Biochemical Pharmacology, , vol. 86, # 9 p. 1366 - 1375
反应条件
dihydrogen peroxide; osmium(VIII) oxide in tert-butyl alcohol 24 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Synthesis, , # 1 p. 45 - 47
