2-氨甲基-5-氯吡啶盐酸盐合成路线 (共 2 条)
反应条件
hydrogenchloride; hydrogen; palladium 10 on activated carbon in ethanol; water P=2068.65 Torr; 2 h;
参考文献
Bristol-Myers Squibb Company
Patent: US2007/129379 A1, 2007 ;
Location in patent: Page/Page column 21-22 ;
反应条件
1: With sodium hydroxide in ethanol T=2°C; 2 h; Inert atmosphere; 2: With hydrogenchloride in water T=18 - 80°C; 3: With sodium hydroxide in water pH=10;
参考文献
WO2011/149921 A1, ;
Page/Page column 88 ;