3,4-二乙酰氧基苯甲醛合成路线 （共 15 条）
反应条件
sodium acetate; acetic anhydride 3 h; Reflux;
参考文献
Pusan National University Industry-University Cooperation Foundation; Chung, Hae Young; Moon, Hyung Ryong; Park, Min Hi; Ha, Young Mi; Park, Yun Jung; Park, Ji Young; Kim, Jin Ah; Lee, Ji Yeon; Lee, Kyung Jin
Patent: US2014/23603 A1, 2014 ;
Location in patent: Paragraph 0234; 0236 ;
参考文献
Pacsu; v.Vargha
Chemische Berichte, 1926 , vol. 59, p. 2819
反应条件
Knoevenagel condensation;
参考文献
Yang, Na; Wang, Qing-He; Wang, Wen-Qian; Wang, Jian; Li, Feng; Tan, Shen-Peng; Cheng, Mao-Sheng
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 53 - 56
反应条件
1: K2CO3; 18-crown-6 / CH2Cl2 / 8 h / 20 °C 2: 10 percent aq. HCl / 6 h / 20 °C 3: KOH / aq. ethanol / 8 h View Scheme
参考文献
Chen, Fang; Kota, Parvathi; Blount, Jack W.; Dixon, Richard A.
Phytochemistry, 2001 , vol. 58, # 7 p. 1035 - 1042
反应条件
1: 2-Amino-5-hydroxy-benzoic acid; acetic anhydride Heating; 2: 3.4-diacetoxybenzaldehyde With toluene-4-sulfonic acid in toluene Heating; 3: With sodium salt of phosphorous acid Heating;
参考文献
Journal of Agricultural and Food Chemistry, , vol. 51, # 3 p. 594 - 600
反应条件
4-(N,N-dimethlyamino)pyridine in dichloromethane
T=20°C; 2 h;
参考文献
Madrid, Alejandro; Espinoza, Luis; Catalan, Karen; Gonzalez, Cesar; Montenegro, Ivan; Mellado, Marco; Werner, Enrique; Cuellar, Mauricio; Villena, Joan
Journal of the Chilean Chemical Society, 2013 , vol. 58, # 3 p. 1814 - 1816
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in dichloromethane
T=0 - 20°C;
参考文献
Fumeaux, Rene; Menozzi-Smarrito, Candice; Stalmach, Angelique; Munari, Caroline; Kraehenbuehl, Karin; Steiling, Heike; Crozier, Alan; Williamson, Gary; Barron, Denis
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 22 p. 5199 - 5211
反应条件
sodium hydroxide in tetrahydrofuran
T=0°C; 0.333333 h;
参考文献
Sawayama, Andrew M.; Tanaka, Hiroko; Wandless, Thomas J.
Journal of Organic Chemistry, 2004 , vol. 69, # 25 p. 8810 - 8820
反应条件
1: (R)-2-amino-1-(3,4-dihydroxyphenyl)ethanol With sodium periodate; phosphate buffer in water
pH=7.4; 0.0833333 h;
2: acetic anhydride With pyridine
参考文献
Manini, Paola; Pezzella, Alessandro; Panzella, Lucia; Napolitano, Alessandra; D'Ischia, Marco
Tetrahedron, 2005 , vol. 61, # 16 p. 4075 - 4080
反应条件
1.1: Pd(OPiv)2; [bis(acetoxy)iodo]benzene / α,α,α-trifluorotoluene / 120 °C / Inert atmosphere
1.2: 20 °C
2.1: pyridine
View Scheme
参考文献
Huang, Chunhui; Ghavtadze, Nugzar; Chattopadhyay, Buddhadeb; Gevorgyan, Vladimir
Journal of the American Chemical Society, 2011 , vol. 133, # 44 p. 17630 - 17633
