2-(4-羟基苯氧基)丙酸合成路线 （共 13 条）
反应条件
potassium hydroxide in ethanol; water T=0°C; 4 h;
参考文献
Kato, Dai-Ichiro; Mitsuda, Satoshi; Ohta, Hiromichi
Journal of Organic Chemistry, 2003 , vol. 68, # 19 p. 7234 - 7242
反应条件
hydrogen bromide in acetic acid
反应条件
hydrogenchloride; sodium sulfate in hexane; water
反应条件
1: 91 percent / sodium hydride / tetrahydrofuran / 14 h / 20 °C 2: 100 percent / hydrogen / Pd/C / ethanol / 5 h / 20 °C 3: 95 percent / potassium hydroxide / ethanol; H2O / 4 h / 0 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 68, # 19 p. 7234 - 7242
反应条件
1: 100 percent / hydrogen / Pd/C / ethanol / 5 h / 20 °C 2: 95 percent / potassium hydroxide / ethanol; H2O / 4 h / 0 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 68, # 19 p. 7234 - 7242
反应条件
1: K2CO3 / dimethylformamide; xylene 2: AcOH / Heating 3: 10 percent aq. NaOH / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 13 p. 1709 - 1713
反应条件
1: K2S2O8 / H2O 2: K2CO3 / dimethylformamide; xylene 3: AcOH / Heating 4: 10 percent aq. NaOH / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 13 p. 1709 - 1713
参考文献
GB916242 , ;
Chem.Abstr., , vol. 59, # 5080
反应条件
chiral stationary phase derived from aminated silica gel, L-2-(p-toluenesulfonamido)-3-phenylpropionyl chloride and dendrimer in hexane; isopropyl alcohol T=25°C; Resolution of racemate;
参考文献
He, Bao-Jiang; Yin, Chuan-Qi; Li, Shi-Rong; Bai, Zheng-Wu
Chirality, 2010 , vol. 22, # 1 p. 69 - 76
反应条件
potassium carbonate in water; dimethyl sulfoxide
参考文献
The Dow Chemical Company
Patent: US4910309 A1, 1990 ;
