4-羟基-6-甲基-2-吡喃酮合成路线 (共 149 条)
反应条件
1: 52 percent / MeONa / benzene / 18 h / Heating 2: conc. H2SO4 / 80 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 22 p. 2715 - 2724
反应条件
T=120 - 130°C; 0.25 h;
参考文献
Liebigs Annalen, , # 4 p. 721 - 724
反应条件
1: With recombinant N-His-tagged hexaketide synthase of Drosophyllum lusitanicum Link T=30°C; pH=7.0; 1 h; aq. bufferEnzymatic reaction; 2: Acidic aq. solution;
参考文献
Phytochemistry, , vol. 69, # 18 p. 3043 - 3053
反应条件
1: With recombinant CazF expressed from S. cerevisiae BJ5464-NpgA2 in aq. phosphate buffer T=20°C; Claisen Condensation; pH=7.4; 1 h; Enzymatic reaction; 2: With sodium hydroxide in water T=65°C; 0.166667 h; Kinetics;
参考文献
Organic Letters, , vol. 15, # 14 p. 3774 - 3777
反应条件
1: 1.) butyl-lithium, di-isopropylamine / 1.) THF, hexane, -78 deg C, 30 min; 2.) THF, hexane, up to RT 2: 94 percent / trifluoroacetic acid, trifluoroacetic anhydride / 0.5 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 755 - 762
反应条件
0.166667 h; Heating;
参考文献
Liebigs Annalen, , # 4 p. 721 - 724
反应条件
Gerbera hybrida 2-pyrone synthase wild type in aq. phosphate buffer T=37°C; pH=6; Enzymatic reaction; Kinetics; Reagent/catalyst;
参考文献
Journal of the American Chemical Society, , vol. 135, # 27 p. 10099 - 10103
反应条件
Multistep reaction. Yields of byproduct given;
参考文献
Chemische Berichte, , vol. 120, p. 1413 - 1420
反应条件
Botrytis cinerea type III polyketide synthase Enzymatic reaction; Kinetics;
参考文献
Molecular BioSystems, , vol. 8, # 11 p. 2864 - 2867,4
反应条件
acetic acid in ethylene glycol dimethyl ether 2 h; Ambient temperature;
参考文献
Moreno-Manas, M.; Papell, E.; Pleixats, R.; Ribas, J.; Virgili, A.
Journal of Heterocyclic Chemistry, 1986 , vol. 23, p. 413 - 416