4,6-二甲基-2-吡喃酮合成路线 （共 35 条）
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in tetrachloromethane 20 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 28, # 8 p. 1831 - 1833
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in tetrachloromethane 20 h; Heating;
参考文献
Shimo, Tetsuro; Ohe, Masayuki; Somekawa, Kenichi; Tsuge, Otohiko
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 8 p. 1831 - 1833
反应条件
(i) , (ii) H2, Raney-Ni; Multistep reaction;
参考文献
Hinnen,A.; Dreux,J.
Bulletin de la Societe Chimique de France, 1964 , p. 1492 - 1498
反应条件
T=-50°C; 17 h; Irradiation;
参考文献
Maier, Guenther; Reisenauer, Hans Peter
Chemische Berichte, 1981 , vol. 114, p. 3916 - 3921
反应条件
2-aminopyridine; hydroxylamine hydrochloride T=70°C; 72 h;
参考文献
ANACOR PHARMACEUTICALS, INC.
Patent: WO2008/64345 A2, 2008 ;
Location in patent: Page/Page column 78-79 ;
参考文献
Diels; Alder
Justus Liebigs Annalen der Chemie, 1931 , vol. 490, p. 257,263
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; lithium diisopropyl amide 1.) THF, -78 deg C, 45 min, 2.) THF; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Dieter, R. Karl; Fishpaugh, Jeffrey R.
Journal of Organic Chemistry, 1987 , vol. 52, # 5 p. 923 - 926
反应条件
T=-50°C; 17 h; Irradiation;
参考文献
Maier, Guenther; Reisenauer, Hans Peter
Chemische Berichte, 1981 , vol. 114, p. 3916 - 3921
反应条件
sodium methylate in methanol T=50°C; Methylation; 2 h;
参考文献
Fehr, Matthias J.; Consiglio, Giambattista; Scalone, Michelangelo; Schmid, Rudolf
Journal of Organic Chemistry, 1999 , vol. 64, # 16 p. 5768 - 5776
参考文献
Journal of Heterocyclic Chemistry, , vol. 29, # 4 p. 811 - 813
