3-烯丙基-4,5-二甲氧基-苯甲醛合成路线 （共 7 条）
反应条件
1: 3,4-dimethoxy-5-iodo-benzaldehyde With di(isobutyl)zinc in 1-methyl-pyrrolidin-2-one; diethyl ether
T=20°C; 3 h;
2: allyl bromide With Li(acac) in 1-methyl-pyrrolidin-2-one; diethyl ether
T=20°C; 5 h;
参考文献
Kneisel, Florian F.; Leuser, Helena; Knochel, Paul
Synthesis, 2005 , # 15 art. no. T08305SS, p. 2625 - 2629
反应条件
potassium carbonate in ethanol
4 h; Reflux;
参考文献
Larghi, Enrique L.; Kaufman, Teodoro S.
Tetrahedron, 2008 , vol. 64, # 42 p. 9921 - 9927
反应条件
N-benzyl-N,N,N-trimethyl-ammonium chloride; sodium hydroxide in water
T=0 - 20°C;
参考文献
Sharma, Nandini; Mohanakrishnan, Dinesh; Sharma, Upendra Kumar; Kumar, Rajesh; Richa; Sinha, Arun Kumar; Sahal, Dinkar
European Journal of Medicinal Chemistry, 2014 , vol. 79, p. 350 - 368
反应条件
1: 88 percent / 1,3,5-trimethyl-benzene / 20 h / Heating
2: 92 percent / K2CO3 / dimethylformamide / 8 h / 20 °C
View Scheme
参考文献
Detterbeck, Richard; Hesse, Manfred
Helvetica Chimica Acta, 2003 , vol. 86, # 2 p. 343 - 360
反应条件
1: 90 percent / K2CO3 / acetone / 8 h / Heating
2: 88 percent / 1,3,5-trimethyl-benzene / 20 h / Heating
3: 92 percent / K2CO3 / dimethylformamide / 8 h / 20 °C
View Scheme
参考文献
Detterbeck, Richard; Hesse, Manfred
Helvetica Chimica Acta, 2003 , vol. 86, # 2 p. 343 - 360
反应条件
methanol; potassium hydroxide; dimethyl sulfate
参考文献
Kawai; Yoshimura
Chemische Berichte, 1938 , vol. 71, p. 2415,2419
反应条件
trichlorophosphate
1) 10 deg C, 45 min 2) r.t., 120 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Narasimhan, N. S.; Mukhopadhyay, T.; Kusurkar, S. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 7 p. 546 - 548
