2-(氰基甲基)-1H-吡咯-3-羧酸乙酯合成路线 （共 3 条）
反应条件
18-crown-6 ether in diethyl ether; water
T=50°C; 6 h;
参考文献
Waly
Bollettino Chimico Farmaceutico, 2000 , vol. 139, # 5 p. 217 - 221
反应条件
1: 86 percent / NBS; benzoylperoxide / CCl4 / 0.25 h / Irradiation
2: 62 percent / 18-crown-6 / H2O; diethyl ether / 6 h / 50 °C
View Scheme
参考文献
Waly
Bollettino Chimico Farmaceutico, 2000 , vol. 139, # 5 p. 217 - 221
反应条件
1: 71.5 percent / hydroxylamine hydrochloride, Na2CO3 / H2O / 1 h / Heating
2: H2 / Raney nickel / H2O / 24 h / 48 - 53 °C / 2327.2 Torr
View Scheme
参考文献
Schneller; Luo; Hosmane
Tetrahedron Letters, 1980 , vol. 21, # 33 p. 3135 - 3138
