2-甲氧基烟酸甲酯合成路线

参考文献

Banner, Bruce Lester; Bilotta, Joseph Anthony; Fotouhi, Nader; Gillespie, Paul; Goodnow, Robert Alan; Hamilton, Matthew Michael; Haynes, Nancy-Ellen; Kowalczyk, Agnieszka; Mayweg, Alexander; Myers, Michael Paul; Pietranico-Cole, Sherrie Lynn; Scott, Nathan Robert; Thakkar, Kshitij Chhabilbhai; Tilley, Jefferson Wright
Patent: US2007/49632 A1, 2007 ;
Location in patent: Page/Page column 38 ;
US 20070049632 A1

67-56-1甲醇+16498-81-02-甲氧基烟酸→67367-26-42-甲氧基烟酸甲酯

参考文献

ALMIRALL, S.A.; EASTWOOD, Paul Robert; GONZALEZ RODRIGUEZ, Jacob; GOMEZ CASTILLO, Elena; BACH TANA, Jordi
Patent: WO2011/157397 A1, 2011 ;
Location in patent: Page/Page column 119 ;

40134-18-72-氯烟酸甲酯→67367-26-42-甲氧基烟酸甲酯

参考文献

SYNGENTA LIMITED
Patent: WO2007/71900 A1, 2007 ;
Location in patent: Page/Page column 94-95 ;

67-56-1甲醇+40134-18-72-氯烟酸甲酯→67367-26-42-甲氧基烟酸甲酯

参考文献

Krawczyk, Soeren; Otto, Monika; Otto, Alexander; Coburger, Claudius; Krug, Martin; Seifert, Marianne; Tell, Volkmar; Molnar, Josef; Higeroth, Andreas
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 21 p. 6309 - 6315

67-56-1甲醇+124-41-4甲醇钠+1452-94-42-氯烟酸乙酯→67367-26-42-甲氧基烟酸甲酯

参考文献

RVX Therapeutics Inc.; McLure, Kevin G.; Young, Peter R.
Patent: US2013/281396 A1, 2013 ;
Location in patent: Paragraph 0305-0306 ;

124-41-4甲醇钠+1452-94-42-氯烟酸乙酯→67367-26-42-甲氧基烟酸甲酯

参考文献

RESVERLOGIX CORP.; JOHANSSON, Jan, O.; HANSEN, Henrik, C.; CHIACCHIA, Fabrizio, S.; WONG, Norman, C.W.
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WO 2007/016525 A2

40134-18-72-氯烟酸甲酯+124-41-4甲醇钠→67367-26-42-甲氧基烟酸甲酯

参考文献

Leroy; Despres; Bigan; Blondeau
Synthetic Communications, 1996 , vol. 26, # 12 p. 2257 - 2272

2942-59-82-氯烟酸→67367-26-42-甲氧基烟酸甲酯

参考文献

Synthetic Communications, , vol. 26, # 12 p. 2257 - 2272

16498-81-02-甲氧基烟酸+18107-18-1三甲基硅烷化重氮甲烷→67367-26-42-甲氧基烟酸甲酯

参考文献

Journal of Medicinal Chemistry, , vol. 43, # 18 p. 3386 - 3399