反应条件
1: 55 percent / PPh3; diethyl azodicarboxylate / tetrahydrofuran / 16 h / 20 °C
2: aq. Ba(OH)2; tetrakis(triphenylphosphine)palladium / benzene; ethanol; 1,2-dimethoxy-ethane / 15 h / 80 °C
View Scheme
参考文献
Tucci, Fabio C.; Zhu, Yun-Fei; Struthers, R. Scott; Guo, Zhiqiang; Gross, Timothy D.; Rowbottom, Martin W.; Acevedo, Oscar; Gao, Yinghong; Saunders, John; Xie, Qiu; Reinhart, Greg J.; Liu, Xin-Jun; Ling, Nicholas; Bonneville, Anne K. L.; Chen, Takung; Bozigrian, Haig; Chen, Chen
Journal of Medicinal Chemistry, 2005 , vol. 48, # 4 p. 1169 - 1178