N-叔丁氧羰基-5-溴-DL-色氨酸合成路线 (共 4 条)
反应条件
sodium hydroxide in 1,4-dioxane 2.5 h; Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 12 p. 3138 - 3142
反应条件
sodium hydroxide in methanol 15 h; Ambient temperature;
参考文献
Synthetic Communications, , vol. 20, # 22 p. 3459 - 3466
反应条件
1: 73 percent / Na2CO3 / CH2Cl2 / 24 h / Ambient temperature 2: 74 percent / zinc / acetic acid / 24 h / Ambient temperature 3: 92 percent / Et3N / 2-methyl-propan-2-ol; H2O / 15 h / Ambient temperature 4: 98 percent / 1M aq. NaOH / methanol / 15 h / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 20, # 22 p. 3459 - 3466
反应条件
1: 74 percent / zinc / acetic acid / 24 h / Ambient temperature 2: 92 percent / Et3N / 2-methyl-propan-2-ol; H2O / 15 h / Ambient temperature 3: 98 percent / 1M aq. NaOH / methanol / 15 h / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 20, # 22 p. 3459 - 3466