2,3,4,5-四氢苯并[c]氮杂-1-酮合成路线 （共 23 条）
反应条件
hydrogenchloride; sodium azide T=0 - 20°C; 24 h;
参考文献
Darras, Fouad H.; Kling, Beata; Heilmann, Joerg; Decker, Michael
ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 11 p. 914 - 919
反应条件
1: With hydrogenchloride; sodium azide in water T=0°C; Schmidt reaction; 0.5 h; 2: With potassium carbonate in water pH=9; Cooling with ice;
参考文献
ChemMedChem, , vol. 5, # 8 p. 1300 - 1317
反应条件
trifluorormethanesulfonic acid T=0 - 70°C; 21 h;
参考文献
Kurouchi, Hiroaki; Kawamoto, Kyoko; Sugimoto, Hiromichi; Nakamura, Satoshi; Otani, Yuko; Ohwada, Tomohiko
Journal of Organic Chemistry, 2012 , vol. 77, # 20 p. 9313 - 9328,16
参考文献
Mazzocchi, P. H.; Wilson, P.; Khachik, F.; Klingler, L.; Minamikawa, S.
Journal of Organic Chemistry, 1983 , vol. 48, # 18 p. 2981 - 2989
反应条件
hydrogenchloride; sodium azide in water T=0 - 50°C; Schmidt reaction;
参考文献
Australian Journal of Chemistry, , vol. 63, # 2 p. 211 - 226
反应条件
tri-n-butyl-tin hydride in toluene 48 h; Reflux;
参考文献
Lee, Su-Jeong; Heo, In-Jung; Cho, Chang-Woo
Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 2 p. 739 - 741
反应条件
thionyl chloride T=50°C; Beckmann rearrangement; 2 h;
参考文献
Crosby, Ian T.; Shin, James K.; Capuano, Ben
Australian Journal of Chemistry, 2010 , vol. 63, # 2 p. 211 - 226
反应条件
hydrogenchloride; sodium azide 4 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 31, # 6 p. 1609 - 1617
反应条件
1: With AlCl3, aluminium chloride in dichloromethane T=-40 - 20°C; Beckmann rearrangement; 1.16667 h; 2: With water
参考文献
ChemMedChem, , vol. 5, # 8 p. 1300 - 1317
反应条件
1: triethylamine / N,N-dimethyl-formamide / 1 h / 0 - 25 °C 2: trifluorormethanesulfonic acid / 21 h / 0 - 70 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 77, # 20 p. 9313 - 9328,16
