BOC-MET-LEU-PHE-OH合成路线 （共 7 条）
反应条件
phosphate buffer in tert-butyl alcohol
T=35°C; alcalase;
参考文献
Chen; Hsiao; Chang; Wang
Synthetic Communications, 1992 , vol. 22, # 3 p. 391 - 398
反应条件
N-benzyl-N,N,N-trimethyl-ammonium chloride in chloroform
3 h; Ambient temperature;
参考文献
Chen; Wang
Journal of the Chemical Society - Series Chemical Communications, 1990 , # 15 p. 1045 - 1047
反应条件
1: DCC; Et3N
2: alcalase; H2O / acetone / pH 8.2
View Scheme
参考文献
Chen, Shui-Tein; Wang, Kung-Tsung
Journal of the Chinese Chemical Society, 1999 , vol. 46, # 3 p. 301 - 311
反应条件
1: diisopropylethylamine / CH2Cl2; dimethylformamide; ethyl acetate / 4 h / Ambient temperature
2: 80 percent / phosphate buffer / 2-methyl-propan-2-ol / 35 °C / alcalase
View Scheme
参考文献
Chen; Hsiao; Chang; Wang
Synthetic Communications, 1992 , vol. 22, # 3 p. 391 - 398
反应条件
1: DCC; Et3N
2: alcalase; H2O / acetone / pH 8.2
3: DCC; Et3N
4: alcalase; H2O / acetone / pH 8.2
View Scheme
参考文献
Chen, Shui-Tein; Wang, Kung-Tsung
Journal of the Chinese Chemical Society, 1999 , vol. 46, # 3 p. 301 - 311
反应条件
1: DCC; Et3N
2: alcalase; H2O / acetone / pH 8.2
3: DCC; Et3N
4: alcalase; H2O / acetone / pH 8.2
View Scheme
参考文献
Chen, Shui-Tein; Wang, Kung-Tsung
Journal of the Chinese Chemical Society, 1999 , vol. 46, # 3 p. 301 - 311
反应条件
HOBt-6-carboxamidomethyl polystyrene; dicyclohexyl-carbodiimide
1.) CH2Cl2, RT, 6 h, 2.) CHCl3, RT, 5 h; Yield given. Multistep reaction;
参考文献
Chen, Shui-Tein; Chang, Chung-Ho; Wang, Kung-Tsung
Journal of Chemical Research, Miniprint, 1991 , # 8 p. 1967 - 1975
