1.1: NaH / tetrahydrofuran / 0.5 h / 0 °C 1.2: 78 percent / tetrahydrofuran / 0 - 20 °C 2.1: 88 percent / Me3FeLi; Mg / tetrahydrofuran / 3 h / 20 °C View Scheme

1.1: NaH / tetrahydrofuran / 1 h / 20 °C 1.2: 83 percent / tetrahydrofuran / 4 h / 20 °C 2.1: 47 percent / (Bu3Sn)2; Et4NI; Li2CO3 / Pd(PPh3)2Cl2 / toluene; dimethylformamide / 6 h / Heating View Scheme

1: methyl lithium View Scheme

暂无反应条件数据

1: 2,2'-Dibromodiphenylamine With n-butyllithium in diethyl ether; hexane T=0°C; 1.5 h; 2: chloro-diphenylphosphine in diethyl ether; hexane T=0 - 20°C;

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0 °C / |Schlenk technique; |Inert atmosphere 1.2: 0 - 20 °C / |Schlenk technique; |Inert atmosphere 2.1: n-butyllithium / hexane; tetrahydrofuran / 1 h / -78 °C / |Schlenk technique; |Inert atmosphere 2.2: -78 - 20 °C / |Schlenk technique; |Inert atmosphere 3.1: potassium tert-butylate / tetrahydrofuran / 0 °C / |Schlenk technique; |Inert atmosphere 4.1: (SPY-5-31)-dichloro-(κ2(C,O)-(2-isopropyloxybenzylidene))(1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene)ruthenium / toluene / 1 h / 100 °C / |Schlenk technique; |Inert atmosphere View Scheme

<b>Multi-step reaction with 2 steps<br /> </b> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11324583', constants.ctx, '0')">1,1'-bis-(diphenylphosphino)ferrocene</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '8402623', constants.ctx, '0')">sodium t-butanolate</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '14221398', constants.ctx, '0')">tris(dibenzylideneacetone)dipalladium ⁽⁰⁾</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '635760', constants.ctx, '0')">toluene</a> <br />T=100&deg;C;&nbsp;Cross-coupling;&nbsp;12&nbsp;h;&nbsp;<br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11342937', constants.ctx, '0')">potassium hydroxide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1718733', constants.ctx, '0')">ethanol</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a> <br />17&nbsp;h;&nbsp;&nbsp;Heating;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 96 percent / PCl₅ / 1) 3 h, room temperature, 2) 1 h, 100 deg C<br />2: 90 percent / NaOEt / diethyl ether / 1) 4 h, 0 deg C, 2) 12 h, room temperature<br />3: 53 percent / 1) 150 min, 260-263 deg C, 2) 40 deg C, 3) ethanol, 0 deg C<br />4: 95 percent / KOH / ethanol; H₂O / 17 h / Heating<br /> <br /> &nbsp;