3,3-二甲基-1-苯基-2-丁酮合成路线 （共 50 条）
反应条件
potassium tert-butylate in dimethyl sulfoxide
T=30 - 35°C; 1.3 h; Irradiationother solvents, time, temperature; Product distribution;
参考文献
Semmelhack, M. F.; Bargar, Thomas
Journal of the American Chemical Society, 1980 , vol. 102, # 26 p. 7765 - 7774
反应条件
pyridine
T=0°C; 2 h;
参考文献
Sakakura, Toshiyasu; Hara, Masayasu; Tanaka, Masato
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 3 p. 283 - 288
反应条件
1: PCl5 / toluene / 3 h / Heating
2: 1.) Li, naphthalene / 1.) THF, -78 deg C, 2.) THF, from -78 deg C to 20 deg C, 3 h.
3: 90 percent / HCl / tetrahydrofuran / 12 h / Ambient temperature
View Scheme
参考文献
Alonso, Emma; Ramon, Diego J.; Yus, Miguel
Tetrahedron, 1998 , vol. 54, # 39 p. 12007 - 12028
反应条件
1: 81 percent / xylene / 16 h / Heating
2: 53 percent / 2N HCl / 6 h / Heating
View Scheme
参考文献
Von Roman; Ruhdorfer; Knorr
Synthesis, 1993 , # 10 p. 985 - 992
反应条件
1: 81 percent / xylene / 16 h / Heating
2: 53 percent / 2N HCl / 6 h / Heating
View Scheme
参考文献
Von Roman; Ruhdorfer; Knorr
Synthesis, 1993 , # 10 p. 985 - 992
反应条件
2: 15 percent / tetrabutylammonium iodide / dimethylformamide / 0 - 10 °C / electrolysis
View Scheme
参考文献
d'Incan, Esther; Sibille, Soline; Perichon, Jacques; Moingeon, Marie-Odile; Chaussard, Jacques
Tetrahedron Letters, 1986 , vol. 27, # 35 p. 4175 - 4176
反应条件
potassium tert-butylate
1) DMSO, 2) RT, 90 min; Yield given. Multistep reaction;
参考文献
Dell'Erba, Carlo; Novi, Marino; Petrillo, Giovanni; Tavani, Cinzia
Tetrahedron, 1992 , vol. 48, # 2 p. 325 - 334
反应条件
in ammonia
T=-33°C; 0.5 h; Irradiationother solvent, time, temperature; Product distribution;
参考文献
Semmelhack, M. F.; Bargar, Thomas
Journal of the American Chemical Society, 1980 , vol. 102, # 26 p. 7765 - 7774
反应条件
in tetrahydrofuran
1) 37 min, -40 deg C 2) 1.8 h, to 6 deg C 3) 5.5 h, r.t.;
参考文献
Chen, Kuanchiang; Koser, Gerald F.
Journal of Organic Chemistry, 1991 , vol. 56, # 20 p. 5764 - 5767
反应条件
copper; copper(l) chloride in diethyl ether
参考文献
Fabre,J.M. et al.
Bulletin de la Societe Chimique de France, 1974 , p. 1473 - 1476
