2’-甲酰(1,1’-联苯)-2-羧酸合成路线 （共 18 条）
反应条件
sodium hydroxide in ethanol; water T=20°C; 24 h;
参考文献
Penhoat, Mael; Leleu, Stephane; Dupas, Georges; Papamicael, Cyril; Marsais, Francis; Levacher, Vincent
Tetrahedron Letters, 2005 , vol. 46, # 48 p. 8385 - 8389
反应条件
ammonium hydroxide; periodic acid T=0 - 20°C;
参考文献
Edwards, David J.; House, David; Sheldrake, Helen M.; Stone, Susan J.; Wallace, Timothy W.
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 16 p. 2658 - 2669
反应条件
1: With oxygen; ozone in dichloromethane T=-30°C; 2: With sodium dithionite in dichloromethane T=-30 - 30°C; 32 h; 3: With hydrogenchloride; water T=5 - 10°C; 2 h;
参考文献
Tyagi, Vipin; Gupta, Ashok Kumar
Synthetic Communications, 2012 , vol. 42, # 6 p. 843 - 848
参考文献
Journal of the American Chemical Society, , vol. 78, p. 3811,3815
Organic Syntheses, , vol. Coll. Vol. V, p. 489
反应条件
1: 2-iodo-benzoyl chloride; DR9HMPA-CH2OH With 4-(N,N-dimethlyamino)pyridine; TEA in pyridine T=20°C; 36 h; 2: 2-formyl-phenyl boronic acid With tetrakis(triphenylphosphine) palladium(0); sodium carbonate in water; N,N-dimethyl-formamide T=110°C; 3: With trifluoroacetic acid in dichloromethane T=20°C; 1 h;
参考文献
Tetrahedron Letters, , vol. 42, # 38 p. 6683 - 6686
反应条件
1: With water; lithium hydroxide hydrate in tetrahydrofuran T=40°C; 2: With hydrogenchloride in tetrahydrofuran; water pH=7;
参考文献
Journal of Organic Chemistry, , vol. 76, # 8 p. 2828 - 2839
反应条件
1: 95 percent / Pd(PPh3)4; K2CO3 / toluene; ethanol; H2O / 6 h / Heating 2: 86 percent / NaOH / ethanol; H2O / 24 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 46, # 48 p. 8385 - 8389
反应条件
1: 94 percent / Pd(PPh3)4; K2CO3 / toluene; ethanol; H2O / 48 h / Heating 2: 91 percent / NBS; AIBN / CCl4 / 6 h / Heating 3: 82 percent / EtONa; 2-nitropropane / ethanol / 10 h / Heating 4: 86 percent / NaOH / ethanol; H2O / 24 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 46, # 48 p. 8385 - 8389
反应条件
1: 82 percent / EtONa; 2-nitropropane / ethanol / 10 h / Heating 2: 86 percent / NaOH / ethanol; H2O / 24 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 46, # 48 p. 8385 - 8389
反应条件
1: 94 percent / Pd(PPh3)4; K2CO3 / toluene; ethanol; H2O / 48 h / Heating 2: 91 percent / NBS; AIBN / CCl4 / 6 h / Heating 3: 82 percent / EtONa; 2-nitropropane / ethanol / 10 h / Heating 4: 86 percent / NaOH / ethanol; H2O / 24 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 46, # 48 p. 8385 - 8389
