2H-吡喃-2-酮-6-羧酸合成路线 （共 7 条）
参考文献
Fried; Elderfield
Journal of Organic Chemistry, 1941 , vol. 6, p. 566,573
反应条件
ammonium acetate; acetic acid
参考文献
Fried; Elderfield
Journal of Organic Chemistry, 1941 , vol. 6, p. 566,573
反应条件
hydrogenchloride; water
T=60 - 100°C; 7 h;
参考文献
NEURIM PHARMACEUTICALS (1991) LTD.
Patent: WO2007/93880 A2, 2007 ;
Location in patent: Page/Page column 37; 38 ;
WO 2007/093880 A2
反应条件
sulfuric acid
T=80°C;
参考文献
Rocca, J. R.; Tumlinson, J. H.; Glancey, B. M.; Lofgren, C. S.
Tetrahedron Letters, 1983 , vol. 24, # 18 p. 1889 - 1892
反应条件
sulfuric acid; acetic acid
参考文献
Rossi; Schinz
Helvetica Chimica Acta, 1948 , vol. 31, p. 473,483
反应条件
thionyl chloride; N,N-dimethyl-formamide
T=85°C;
参考文献
Rocca, J. R.; Tumlinson, J. H.; Glancey, B. M.; Lofgren, C. S.
Tetrahedron Letters, 1983 , vol. 24, # 18 p. 1889 - 1892
反应条件
1: thionyl chloride
View Scheme
参考文献
Wiley; Hart
Journal of the American Chemical Society, 1954 , vol. 76, p. 1942
