2-氨基-2-氰基乙酰胺合成路线 (共 17 条)
反应条件
ammonia in methanol T=0 - 5°C; 1 h;
参考文献
IND-SWIFT LABORATORIES LIMITED; BHIRUD, Shekhar Bhaskar; SARIN, Gurdeep Singh; GUPTA, Neeraj; TIWARI, Parveen Kumar; CHIDAMBARAM, Venkateswaran Srinivasan; WADHWA, Lalit
Patent: WO2010/140168 A1, 2010 ;
Location in patent: Page/Page column 14 ;
反应条件
hydrogenchloride; ammonia; hydrogen; sodium nitrite in methanol; water; acetic acid
反应条件
ammonia in methanol; (2S)-N-methyl-1-phenylpropan-2-amine hydrate; toluene
参考文献
Pfizer Inc
Patent: US5734053 A1, 1998 ;
US 5734053 A
反应条件
nickel Hydrogenation;
参考文献
Journal of the American Chemical Society, , vol. 74, p. 2892
参考文献
Journal of the Chemical Society, , p. 1440
参考文献
Journal of the Chemical Society, , p. 1440
反应条件
1: orthoformic acid triethyl ester; α-amino-α-cyanoacetamide in acetonitrile 0.75 h; Reflux; 2: 1-amino diphenylmethane in acetonitrile 0.75 h; Reflux;
参考文献
Chattopadhyay, Gautam; Ray, Parlha Sinha
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2013 , vol. 52, # 4 p. 546 - 552
参考文献
Miller et al.
Journal of the American Chemical Society, 1952 , vol. 74, p. 2892
反应条件
in acetonitrile 0.75 h; Heating;
参考文献
Sen, A. K.; Mukhopadhyay, Ajoy Kumar
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 4 p. 275 - 278