螺[1,3-二氧戊环-2,1'-茚]合成路线 （共 5 条）
反应条件
toluene-4-sulfonic acid in tetrahydrofuran; water 6 h; Ambient temperature;
参考文献
Zimmerman, Howard E.; Factor, Ronda E.
Journal of the American Chemical Society, 1980 , vol. 102, # 10 p. 3538 - 3548
反应条件
potassium tert-butylate
T=90°C; 3 h; Yield given;
参考文献
Allen, Annette D.; Fujio, Mizue; Mohammed, Nageib; Tidwell, Thomas T.; Tsuji, Yutaka
Journal of Organic Chemistry, 1997 , vol. 62, # 2 p. 246 - 252
反应条件
1: toluenesulfonic acid monohydrate / toluene / 5 h / Heating
2: t-BuOK / 3 h / 90 °C
View Scheme
参考文献
Allen, Annette D.; Fujio, Mizue; Mohammed, Nageib; Tidwell, Thomas T.; Tsuji, Yutaka
Journal of Organic Chemistry, 1997 , vol. 62, # 2 p. 246 - 252
反应条件
1: (i) benzene-1,4-diol, (ii) aq. HCl, EtOH, H2O
2: 1-isopropyl-4-methyl-benzene / Pd-C
3: diethyl ether; methanol
View Scheme
参考文献
House,H.O. et al.
Journal of the American Chemical Society, 1960 , vol. 82, p. 1463 - 1466
反应条件
1: (i) benzene-1,4-diol, (ii) aq. HCl, EtOH, H2O
2: 1-isopropyl-4-methyl-benzene / Pd-C
View Scheme
参考文献
House,H.O. et al.
Journal of the American Chemical Society, 1960 , vol. 82, p. 1463 - 1466
