5-氟-4-疏基-2-羟基嘧啶合成路线 （共 4 条）
反应条件
diphosphorus pentasulfide; sodium hydrogencarbonate in diethylene glycol dimethyl ether T=110°C; 3 h;
参考文献
Lapucha, Andrzej R.
Synthesis, 1987 , # 3 p. 256 - 258
反应条件
diphosphorus pentasulfide in 1,4-dioxane; water
参考文献
Mead Johnson and Company
Patent: US4581357 A1, 1986 ;
反应条件
thionyl chloride 12 h; Ambient temperature;
参考文献
Yamashita; Yamawaki; Ueda; Yasumoto; Unemi; Hashimoto
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 12 p. 4258 - 4267
反应条件
ammonium hydroxide; nickel 1 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 34, # 11 p. 3280 - 3284
