2-乙酰氨基-5-甲基苯甲酸合成路线 （共 13 条）
反应条件
Yield given. Multistep reaction;
参考文献
Patil; Jones; Nair; Galivan; Maley; Kisliuk; Gaumont; Duch; Ferone
Journal of Medicinal Chemistry, 1989 , vol. 32, # 6 p. 1284 - 1289
反应条件
2: 50 percent / 2,4-dibromo-5,5-dimethylhydantoin / benzoyl peroxide / CCl4; CHCl3 / 18 h / Heating; Irradiation View Scheme
参考文献
Patil; Jones; Nair; Galivan; Maley; Kisliuk; Gaumont; Duch; Ferone
Journal of Medicinal Chemistry, 1989 , vol. 32, # 6 p. 1284 - 1289
反应条件
1: 35 percent / 1,3-dibromo-5,5-dimethylhydantoin / CCl4; CHCl3 / Heating; Irradiation 2: 87 percent / MgO / N,N-dimethyl-acetamide / 18 h / 90 - 100 °C View Scheme
参考文献
Patil; Jones; Nair; Galivan; Maley; Kisliuk; Gaumont; Duch; Ferone
Journal of Medicinal Chemistry, 1989 , vol. 32, # 6 p. 1284 - 1289
反应条件
2: 50 percent / 2,4-dibromo-5,5-dimethylhydantoin / benzoyl peroxide / CCl4; CHCl3 / 18 h / Heating; Irradiation 3: 67 percent / MgO / N,N-dimethyl-acetamide / 16 h / 90 - 100 °C View Scheme
参考文献
Patil; Jones; Nair; Galivan; Maley; Kisliuk; Gaumont; Duch; Ferone
Journal of Medicinal Chemistry, 1989 , vol. 32, # 6 p. 1284 - 1289
反应条件
water; palladium diacetate; toluene-4-sulfonic acid; p-benozquinone in acetic acid; toluene
T=20 - 60°C; P=760.051 Torr;
参考文献
Giri, Ramesh; Lam, Jonathan K.; Yu, Jin-Quan
Journal of the American Chemical Society, 2010 , vol. 132, # 2 p. 686 - 693
反应条件
Acetylation; 1 h; Heating;
参考文献
Osborne, Alan G.; Goolamali, Zia
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2000 , vol. 56, # 6 p. 1079 - 1100
反应条件
sodium hydroxide; oxygen; rose bengal in methanol
T=5 - 10°C; 1 h; Irradiation;
参考文献
Staskun, Benjamin
Journal of Organic Chemistry, 1988 , vol. 53, # 22 p. 5287 - 5291
反应条件
potassium permanganate in water
T=80°C;
参考文献
Chen, Shiyan; Lin, Jimao; Qin, Bingjie
Organic Preparations and Procedures International, 2004 , vol. 36, # 3 p. 277 - 279
反应条件
dihydrogen peroxide in methanol; sodium hydroxide
0.25 h; Yield given;
参考文献
Staskun, Benjamin
Journal of Organic Chemistry, 1988 , vol. 53, # 22 p. 5287 - 5291
反应条件
dihydrogen peroxide; acetic acid
参考文献
Cardani; Piozzi
Gazzetta Chimica Italiana, 1956 , vol. 86, p. 849,862
